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Ub-SMAD4:USP9X [cytosol]
Stable Identifier
R-HSA-870520
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Homo sapiens)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Homo sapiens)
USP9X (FAM) binds to ubiquitinated SMAD4 (Homo sapiens)
Ub-SMAD4:USP9X [cytosol] (Homo sapiens)
USP9X (FAM) deubiquitinates SMAD4 (Homo sapiens)
Ub-SMAD4:USP9X [cytosol] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
USP9X (FAM) binds to ubiquitinated SMAD4 (Homo sapiens)
Ub-SMAD4:USP9X [cytosol] (Homo sapiens)
USP9X (FAM) deubiquitinates SMAD4 (Homo sapiens)
Ub-SMAD4:USP9X [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by TGF-beta family members (Homo sapiens)
Signaling by TGF-beta Receptor Complex (Homo sapiens)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Homo sapiens)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Homo sapiens)
USP9X (FAM) binds to ubiquitinated SMAD4 (Homo sapiens)
Ub-SMAD4:USP9X [cytosol] (Homo sapiens)
USP9X (FAM) deubiquitinates SMAD4 (Homo sapiens)
Ub-SMAD4:USP9X [cytosol] (Homo sapiens)
Participants
components
SMAD4 [cytosol] (Homo sapiens)
Ub [cytosol] (Homo sapiens)
USP9X [cytosol] (Homo sapiens)
Participant Of
input
USP9X (FAM) deubiquitinates SMAD4
output
USP9X (FAM) binds to ubiquitinated SMAD4
Inferred To
Ub-SMAD4:USP9X [cytosol] (Bos taurus)
Ub-SMAD4:USP9X [cytosol] (Caenorhabditis elegans)
Ub-SMAD4:USP9X [cytosol] (Canis familiaris)
Ub-SMAD4:USP9X [cytosol] (Danio rerio)
Ub-SMAD4:USP9X [cytosol] (Drosophila melanogaster)
Ub-SMAD4:USP9X [cytosol] (Gallus gallus)
Ub-SMAD4:USP9X [cytosol] (Mus musculus)
Ub-SMAD4:USP9X [cytosol] (Rattus norvegicus)
Ub-SMAD4:USP9X [cytosol] (Sus scrofa)
Ub-SMAD4:USP9X [cytosol] (Xenopus tropicalis)
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