trans-Hexadec-2-enoyl-CoA+H2O => (S)-3-Hydroxyhexadecanoyl-CoA

Stable Identifier
R-HSA-77301
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
(2E)-hexadecenoyl-CoA + H2O => (3S)-hydroxyhexadecanoyl-CoA
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
trans-Hexadec-2-enoyl-CoA+H2O => (S)-3-Hydroxyhexadecanoyl-CoA
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Trifunctional protein in the mitochondrial matrix hydrates trans-hexadec-2-enoyl-CoA to form (S)-3-hydroxyhexadecanoyl-CoA (Carpenter et al. 1992).
Literature References
PubMed ID Title Journal Year
1550553 Human liver long-chain 3-hydroxyacyl-coenzyme A dehydrogenase is a multifunctional membrane-bound beta-oxidation enzyme of mitochondria.

Carpenter, K, Pollitt, RJ, Middleton, B

Biochem Biophys Res Commun 1992
Participants
Input
Output
Participates
as an event of
Catalyst Activity

enoyl-CoA hydratase activity of Trifunctional Protein [mitochondrial matrix]

Physical Entity
Trifunctional Protein [mitochondrial matrix] (Homo sapiens)
Activity
enoyl-CoA hydratase activity (GO:0004300)
Orthologous Events
trans-Hexadec-2-enoyl-CoA+H2O => (S)-3-Hydroxyhexadecanoyl-CoA (Bos taurus)
trans-Hexadec-2-enoyl-CoA+H2O => (S)-3-Hydroxyhexadecanoyl-CoA (Caenorhabditis elegans)
trans-Hexadec-2-enoyl-CoA+H2O => (S)-3-Hydroxyhexadecanoyl-CoA (Canis familiaris)
trans-Hexadec-2-enoyl-CoA+H2O => (S)-3-Hydroxyhexadecanoyl-CoA (Danio rerio)
trans-Hexadec-2-enoyl-CoA+H2O => (S)-3-Hydroxyhexadecanoyl-CoA (Drosophila melanogaster)
trans-Hexadec-2-enoyl-CoA+H2O => (S)-3-Hydroxyhexadecanoyl-CoA (Gallus gallus)
trans-Hexadec-2-enoyl-CoA+H2O => (S)-3-Hydroxyhexadecanoyl-CoA (Mus musculus)
trans-Hexadec-2-enoyl-CoA+H2O => (S)-3-Hydroxyhexadecanoyl-CoA (Rattus norvegicus)
trans-Hexadec-2-enoyl-CoA+H2O => (S)-3-Hydroxyhexadecanoyl-CoA (Sus scrofa)
trans-Hexadec-2-enoyl-CoA+H2O => (S)-3-Hydroxyhexadecanoyl-CoA (Xenopus tropicalis)
Cross References
RHEA
Created
Gillespie, ME  (2003-09-19)
Cite Us!