dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK]

Stable Identifier
R-HSA-75126
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK]
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Cytosolic deoxythymidylate kinase (DTYMK) catalyzes the reversible reaction of either dUDP or TDP with ADP to form dUMP or TMP. The active form of the enzyme is a homodimer (Lee and Cheng 1977).

Literature References
Participants
Input
Output
Participant Of
hasEvent
Event Information
Reverse Reaction
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Homo sapiens)
Catalyst Activity
Catalyst Activity
Title
nucleoside monophosphate kinase activity of DTYMK dimer [cytosol]
Physical Entity
DTYMK dimer [cytosol]
Activity
nucleoside monophosphate kinase activity (0050145)
Orthologous Events
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Bos taurus)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Caenorhabditis elegans)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Canis familiaris)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Danio rerio)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Dictyostelium discoideum)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Drosophila melanogaster)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Gallus gallus)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Mus musculus)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Plasmodium falciparum)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Rattus norvegicus)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Saccharomyces cerevisiae)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Schizosaccharomyces pombe)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Sus scrofa)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Xenopus tropicalis)
Created
D'Eustachio, P  (2003-08-25)