dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK]

Stable Identifier
R-HSA-75126
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK]
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Cytosolic deoxythymidylate kinase (DTYMK) catalyzes the reversible reaction of either dUDP or TDP with ADP to form dUMP or TMP. The active form of the enzyme is a homodimer (Lee and Cheng 1977).
Literature References
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Event Information
Reverse Reaction
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Homo sapiens)
Catalyst Activity

nucleoside monophosphate kinase activity of DTYMK dimer [cytosol]

Physical Entity
DTYMK dimer [cytosol] (Homo sapiens)
Activity
nucleoside monophosphate kinase activity (GO:0050145)
Orthologous Events
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Bos taurus)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Caenorhabditis elegans)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Canis familiaris)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Danio rerio)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Dictyostelium discoideum)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Drosophila melanogaster)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Gallus gallus)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Mus musculus)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Plasmodium falciparum)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Rattus norvegicus)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Saccharomyces cerevisiae)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Schizosaccharomyces pombe)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Sus scrofa)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Xenopus tropicalis)
Cross References
Rhea
Created
D'Eustachio, P  (2003-08-25)
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