Binding of ADAR1 homodimer to dsRNA duplex

Stable Identifier
R-HSA-75090
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Binding of ADAR1 homodimer to dsRNA duplex
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At the beginning of this reaction, 1 molecule of 'dsRNA duplex', and 1 molecule of 'ADAR1 homodimer ' are present. At the end of this reaction, 1 molecule of 'Editosome (ADAR1) complex' is present.

This reaction takes place in the 'nucleus' (Cho et al. 2003).
Literature References
PubMed ID Title Journal Year
12618436 Requirement of dimerization for RNA editing activity of adenosine deaminases acting on RNA

Yang, W, Cho, DS, Murray, JM, Lee, JT, Shiekhattar, R, Nishikura, K

J. Biol. Chem. 2003
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Orthologous Events
Binding of ADAR1 homodimer to dsRNA duplex (Bos taurus)
Binding of ADAR1 homodimer to dsRNA duplex (Canis familiaris)
Binding of ADAR1 homodimer to dsRNA duplex (Gallus gallus)
Binding of ADAR1 homodimer to dsRNA duplex (Mus musculus)
Binding of ADAR1 homodimer to dsRNA duplex (Rattus norvegicus)
Binding of ADAR1 homodimer to dsRNA duplex (Sus scrofa)
Created
Carmichael, GG  (2003-12-05)
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