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Formation of editosomes by ADAR proteins
Stable Identifier
R-HSA-77042
Type
Pathway
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Metabolism of RNA (Homo sapiens)
mRNA Editing (Homo sapiens)
mRNA Editing: A to I Conversion (Homo sapiens)
Formation of editosomes by ADAR proteins (Homo sapiens)
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It is still unclear how ADAR 1 and ADAR 2 proteins form the editosomes with the target RNA. Other components of these editosomes for A to I editing are unknown.
Participants
Events
Formation of ADAR1 homodimer
(Homo sapiens)
Binding of ADAR1 homodimer to dsRNA duplex
(Homo sapiens)
Formation of ADAR2 homodimer
(Homo sapiens)
Binding of ADAR2 homodimer to dsRNA duplex
(Homo sapiens)
Participates
as an event of
mRNA Editing: A to I Conversion (Homo sapiens)
Orthologous Events
Formation of editosomes by ADAR proteins (Bos taurus)
Formation of editosomes by ADAR proteins (Caenorhabditis elegans)
Formation of editosomes by ADAR proteins (Canis familiaris)
Formation of editosomes by ADAR proteins (Drosophila melanogaster)
Formation of editosomes by ADAR proteins (Gallus gallus)
Formation of editosomes by ADAR proteins (Mus musculus)
Formation of editosomes by ADAR proteins (Rattus norvegicus)
Formation of editosomes by ADAR proteins (Sus scrofa)
Formation of editosomes by ADAR proteins (Xenopus tropicalis)
Authored
Gopinathrao, G (2003-12-05)
Created
Carmichael, GG (2003-12-05)
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