Hydroxymethylglutaryl-CoA lyase dimer (HMGCL) in the mitochondrial matrix catalyzes the reaction of beta-hydroxy-beta-methylglutaryl coenzyme A (HMG CoA) to form acetyl-CoA and acetoacetate (Mitchell et al. 1993).
Hruz, PW, Wang, S, Schappert, K, Mende-Mueller, LM, Behnke, CE, Gibson, KM, Miziorko, HM, Lee, C, Robert, MF, Mitchell, GA, Fontaine, G
hydroxymethylglutaryl-CoA lyase activity of HMGCL dimer [mitochondrial matrix]
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