Hydroxymethylglutaryl-CoA lyase dimer (HMGCL) in the mitochondrial matrix catalyzes the reaction of beta-hydroxy-beta-methylglutaryl coenzyme A (HMG CoA) to form acetyl-CoA and acetoacetate (Mitchell et al. 1993).
Mitchell, GA, Robert, MF, Hruz, PW, Wang, S, Fontaine, G, Behnke, CE, Mende-Mueller, LM, Schappert, K, Lee, C, Gibson, KM, Miziorko, HM
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