Reactome | TALDO1 [cytosol]

TALDO1 [cytosol]

Stable Identifier

R-HSA-71325

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

transaldolase 1

Locations in the PathwayBrowser

Expand all

Cellular responses to stimuli (Homo sapiens)

- Cellular responses to stress (Homo sapiens)
  - Cellular response to chemical stress (Homo sapiens)
    - KEAP1-NFE2L2 pathway (Homo sapiens)
      - Nuclear events mediated by NFE2L2 (Homo sapiens)
        
        NFE2L2 regulates pentose phosphate pathway genes (Homo sapiens)
        
        NFE2L2-dependent TALDO1 gene expression (Homo sapiens)
        
        TALDO1 dimer [cytosol] (Homo sapiens)
        
        TALDO1 [cytosol] (Homo sapiens)

Immune System (Homo sapiens)

- Cytokine Signaling in Immune system (Homo sapiens)
  - Signaling by Interleukins (Homo sapiens)
    - Interleukin-12 family signaling (Homo sapiens)
      - Interleukin-12 signaling (Homo sapiens)
        
        Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation (Homo sapiens)
        
        Expression of transaldolase 1 (Homo sapiens)
        
        TALDO1 [cytosol] (Homo sapiens)

Literature References

PubMed ID	Title	Journal	Year
11283793	Transaldolase deficiency: liver cirrhosis associated with a new inborn error in the pentose phosphate pathway. Verhoeven, NM, Huck, JHJ, Roos, B, Struys, EA, Salomons, GS, Douwes, AC, van der Knaap, MS, Jakobs, C	Am J Hum Genet	2001

External Reference Information

External Reference

UniProt:P37837 TALDO1

Gene Names

TALDO1, TAL, TALDO, TALDOR

Chain

chain:1-337

Reference Genes

BioGPS Gene:6888 TALDO1

COSMIC - genes:TALDO1 TALDO1

CTD Gene:6888 TALDO1

dbSNP Gene:6888 TALDO1

ENSEMBL:ENSG00000177156 TALDO1

HGNC:11559 TALDO1

KEGG:hsa:6888 TALDO1

Monarch:6888 TALDO1

NCBI Gene:6888 TALDO1

OMIM:602063 TALDO1

UCSC:P37837 TALDO1

Reference Transcript

RefSeq:NM_006755.2 TALDO1

Other Identifiers

11715447_at

11761067_at

16720318

201463_PM_s_at

201463_s_at

3316210

3316211

3316212

3316213

3316214

3316215

3316216

3316217

3316218

3316219

3316221

3316222

3316223

3316224

3316225

3316226

3316227

37311_at

6888

7937465

A_23_P44993

A_24_P81740

GE58421

GO:0004801

GO:0005515

GO:0005634

GO:0005737

GO:0005829

GO:0005975

GO:0006002

GO:0006091

GO:0006098

GO:0009052

GO:0016740

GO:0019682

GO:0030246

GO:0048029

GO:0055086

GO:0070062

GO:1901135

HMNXSV003056231

ILMN_1670998

ILMN_1746588

L19437_at

PH_hs_0025684

TC11000027.hg

g5803186_3p_a_at

Participates

as an output of

Expression of transaldolase 1 (Homo sapiens)

as a component of

TALDO1 dimer [cytosol] (Homo sapiens)

Other forms of this molecule

TALDO1 R192C [cytosol]

TALDO1 R192H [cytosol]

TALDO1 S171F [cytosol]

Inferred To

TAL1 [cytosol] (Saccharomyces cerevisiae)

tal1 [cytosol] (Schizosaccharomyces pombe)

taldo1 [cytosol] (Danio rerio)

taldo1 [cytosol] (Xenopus tropicalis)

tald-1 [cytosol] (Caenorhabditis elegans)

Taldo1 [cytosol] (Mus musculus)

Taldo1 [cytosol] (Rattus norvegicus)

Taldo [cytosol] (Drosophila melanogaster)

TALDO1 [cytosol] (Bos taurus)

TALDO1 [cytosol] (Canis familiaris)

TALDO1 [cytosol] (Gallus gallus)

TALDO1 [cytosol] (Sus scrofa)

tal [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

NP_006746.1

ENSEMBL

ENST00000319006, ENSG00000177156, ENSP00000321259

OpenTargets

ENSG00000177156

GeneCards

TALDO1

HPA

ENSG00000177156-TALDO1

PRO

P37837

Pharos - Targets

P37837

GlyGen

P37837

Orphanet

TALDO1

HMDB Protein

HMDBP00802

PDB

1F05

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:Q9NYB0 TERF2IP	1	TERF2IP [nucleoplasm] (R-HSA-174873)	0.508	2