Trimerization of the FASL:FAS receptor complex

Stable Identifier
R-HSA-71050
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Trimerization of the FASL:FAS receptor complex
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The complex of FASL (FAS antigen ligand) and FAS receptor (CD95) trimerizes (Kischkel et al. 1995).
Literature References
PubMed ID Title Journal Year
8521815 Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor

Pawlita, M, Behrmann, I, Germer, M, Peter, ME, Hellbardt, S, Kischkel, FC, Krammer, PH

EMBO J 1995
Participants
Input
Output
Participates
as an event of
Orthologous Events
Trimerization of the FASL:FAS receptor complex (Bos taurus)
Trimerization of the FASL:FAS receptor complex (Canis familiaris)
Trimerization of the FASL:FAS receptor complex (Gallus gallus)
Trimerization of the FASL:FAS receptor complex (Mus musculus)
Trimerization of the FASL:FAS receptor complex (Rattus norvegicus)
Trimerization of the FASL:FAS receptor complex (Sus scrofa)
Trimerization of the FASL:FAS receptor complex (Xenopus tropicalis)
Reviewed
Salvesen, GS  (2013-05-22)
Pop, C  (2013-05-22)
Created
Tschopp, J  (2004-01-28)
Cite Us!