Trimerization of the FASL:FAS receptor complex

Stable Identifier
R-HSA-71050
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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Trimerization of the FASL:FAS receptor complex
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The complex of FASL (FAS antigen ligand) and FAS receptor (CD95) trimerizes (Kischkel et al. 1995).

Literature References
PubMed ID Title Journal Year
8521815 Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor

Pawlita, M, Behrmann, I, Germer, M, Peter, ME, Hellbardt, S, Kischkel, FC, Krammer, PH

EMBO J 1995
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Orthologous Events
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Trimerization of the FASL:FAS receptor complex (Mus musculus)
Trimerization of the FASL:FAS receptor complex (Rattus norvegicus)
Trimerization of the FASL:FAS receptor complex (Sus scrofa)
Trimerization of the FASL:FAS receptor complex (Xenopus tropicalis)
Reviewed
Salvesen, GS  (2013-05-22)
Pop, C  (2013-05-22)
Created
Tschopp, J  (2004-01-28)
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