histidine => urocanate + NH4+

Stable Identifier
R-HSA-70899
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
L-histidine => NH4(+) + trans-urocanate
ReviewStatus
5/5
Locations in the PathwayBrowser
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Cytosolic histidine ammonia lyase (HAL) catalyzes the reaction of histidine to form urocanate and NH4+ (Kawai et al. 2005).
Literature References
PubMed ID Title Journal Year
15806399 Molecular characterization of histidinemia: identification of four missense mutations in the histidase gene

Asai, K, Sumi, S, Coleman-Campbell, CM, Morishita, H, Moriyama, A, Kawai, Y, Suchi, M

Hum Genet 2005
Participants
Participates
Catalyst Activity

histidine ammonia-lyase activity of HAL [cytosol]

Orthologous Events
Cross References
RHEA
Rhea
Authored
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