methacrylyl-CoA + H2O <=> beta-hydroxyisobutyryl-CoA

Stable Identifier
R-HSA-70870
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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The reversible reaction of methacrylyl-CoA and water to form beta-hydroxybutyryl-CoA takes place in the mitochondrial matrix. While crude extracts of human fibroblasts and liver cells have been shown to catalyze the reaction, the specific human enzyme responsible for it has not been identified.

Literature References
PubMed ID Title Journal Year
  The Metabolic and Molecular Bases of Inherited Disease, 8th ed

Scriver, CR, Beaudet, AL, Valle, D, Sly, WS

  2001
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
enoyl-CoA hydratase activity of enoyl-CoA hydratase [mitochondrial matrix]
Physical Entity
Activity
Cross References
Rhea