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PFKM [cytosol]
Stable Identifier
R-HSA-70460
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
6-phosphofructokinase, muscle type , Phosphofructokinase 1, Phosphohexokinase, Phosphofructo-1-kinase isozyme A, PFK-A, Phosphofructokinase-M
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glucose metabolism (Homo sapiens)
Glycolysis (Homo sapiens)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Homo sapiens)
PFK tetramer [cytosol] (Homo sapiens)
phosphofructokinase, M2L2 complex [cytosol] (Homo sapiens)
PFKM [cytosol] (Homo sapiens)
phosphofructokinase, M3L complex [cytosol] (Homo sapiens)
PFKM [cytosol] (Homo sapiens)
phosphofructokinase, M4 complex [cytosol] (Homo sapiens)
PFKM [cytosol] (Homo sapiens)
phosphofructokinase, ML3 complex [cytosol] (Homo sapiens)
PFKM [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P08237 PFKM
Gene Names
PFKM, PFKX
Chain
initiator methionine:, chain:2-780
Reference Genes
BioGPS Gene:5213 PFKM
COSMIC (genes):PFKM PFKM
CTD Gene:5213 PFKM
dbSNP Gene:5213 PFKM
ENSEMBL:ENSG00000152556 PFKM
HGNC:8877 PFKM
KEGG:hsa:5213 PFKM
Monarch:5213 PFKM
NCBI Gene:5213 PFKM
OMIM:610681 PFKM
UCSC:P08237 PFKM
Reference Transcript
RefSeq:XM_005268979.1 PFKM
RefSeq:NM_001166687.1 PFKM
RefSeq:XM_005268977.1 PFKM
RefSeq:NM_001166688.1 PFKM
RefSeq:XM_005268978.2 PFKM
RefSeq:NM_000289.5 PFKM
RefSeq:XM_011538488.2 PFKM
RefSeq:NM_001166686.1 PFKM
RefSeq:XM_017019468.1 PFKM
Other Identifiers
11716202_a_at
16750523
210976_PM_s_at
210976_s_at
3413345
3413346
3413347
3413348
3413349
3413351
3413352
3413353
3413354
3413355
3413356
3413358
3413359
3413360
3413361
3413362
3413363
3413364
3413365
3413366
3413367
3413368
3413369
3413370
3413371
3413372
3413374
3413375
3413376
3413377
3413378
3413379
3413380
3413381
3413382
3413383
3413384
3413385
3413386
3413387
3413388
3413389
3413390
3413391
3413392
3413393
3413395
3413397
36196_at
5213
7955078
A_14_P126910
A_24_P98914
GE59024
GO:0003824
GO:0003872
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0005945
GO:0005975
GO:0005980
GO:0006002
GO:0006091
GO:0006096
GO:0006355
GO:0008443
GO:0016020
GO:0016208
GO:0016301
GO:0016324
GO:0016740
GO:0019900
GO:0030388
GO:0032024
GO:0042593
GO:0042802
GO:0043226
GO:0045944
GO:0046716
GO:0046835
GO:0046872
GO:0048029
GO:0055086
GO:0061615
GO:0061621
GO:0070061
GO:0070095
GO:0093001
GO:0097228
GO:1901135
HMNXSV003031385
HMNXSV003033380
ILMN_2043809
PH_hs_0004281
TC12000346.hg
U24183_s_at
g975289_3p_a_at
Participates
as a component of
phosphofructokinase, M2L2 complex [cytosol] (Homo sapiens)
phosphofructokinase, ML3 complex [cytosol] (Homo sapiens)
phosphofructokinase, M4 complex [cytosol] (Homo sapiens)
phosphofructokinase, M3L complex [cytosol] (Homo sapiens)
Inferred To
PFKM [cytosol]
(Bos taurus)
PFKM [cytosol]
(Canis familiaris)
PFKM [cytosol]
(Danio rerio)
PFKM [cytosol]
(Gallus gallus)
PFKM [cytosol]
(Mus musculus)
PFKM [cytosol]
(Rattus norvegicus)
PFKM [cytosol]
(Sus scrofa)
PFKL [cytosol]
(Caenorhabditis elegans)
PFKL [cytosol]
(Drosophila melanogaster)
PFKL [cytosol]
(Saccharomyces cerevisiae)
PFKL [cytosol]
(Schizosaccharomyces pombe)
Cross References
RefSeq
XP_005269034.1
,
XP_005269036.1
,
XP_016874957.1
,
NP_001160158.1
,
NP_001160159.1
,
NP_001160160.1
,
XP_005269035.1
,
XP_011536790.1
,
NP_000280.1
OpenTargets
ENSG00000152556
ENSEMBL
ENST00000550345
,
ENST00000547587
,
ENST00000340802
,
ENST00000359794
,
ENST00000551339
,
ENSP00000352842
,
ENSP00000309438
,
ENSP00000446945
,
ENST00000550924
,
ENSP00000345771
,
ENST00000551804
,
ENSP00000450369
,
ENSP00000448253
,
ENSP00000448177
,
ENST00000312352
,
ENSP00000449426
HPA
ENSG00000152556-PFKM
ZINC - Substances
PFKAM_HUMAN
ZINC target
P08237
PRO
P08237
Pharos - Targets
P08237
Orphanet
PFKM
GlyGen
P08237
PDB
4OMT
HMDB Protein
HMDBP00762
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8IUQ4 SIAH1
1
SIAH1 [cytosol]
(R-HSA-374563)
0.556
3
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