Formation of Cyclin E:Cdk2 complexes

Stable Identifier
Reaction [binding]
Homo sapiens
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The E-type cyclins and Cyclin Dependent Kinase 2 control the transition from G1 to S phase. Cdk2 is competent to carry out the necessary reactions only when complexed with Cyclin E.

Literature References
PubMed ID Title Journal Year
7799941 Effects of phosphorylation by CAK on cyclin binding by CDC2 and CDK2.

Desai, D, Wessling, HC, Fisher, RP, Morgan, DO

Mol Cell Biol 1995
Participant Of
Orthologous Events
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