Recruitment of Dna2 endonuclease

Stable Identifier
R-HSA-69142
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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Recruitment of Dna2 endonuclease
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After RPA binds the long flap, it recruits the Dna2 endonuclease. Dna2 endonuclease removes most of the flap, but the job of complete removal of the flap is then completed by FEN-1.

Literature References
PubMed ID Title Journal Year
11473323 RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes.

Seo, YS, Bae, SH, Bae, KH, Kim, JA

Nature 2001
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