Recruitment of Dna2 endonuclease

Stable Identifier
Reaction [binding]
Homo sapiens
Locations in the PathwayBrowser
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

After RPA binds the long flap, it recruits the Dna2 endonuclease. Dna2 endonuclease removes most of the flap, but the job of complete removal of the flap is then completed by FEN-1.

Literature References
PubMed ID Title Journal Year
11473323 RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes.

Bae, SH, Bae, KH, Kim, JA, Seo, YS

Nature 2001
Participant Of
Orthologous Events
Cite Us!