ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation

Stable Identifier
R-HSA-6814670
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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ATP hydrolysis by RHOBTB is thought to promote uncoating of the late endosome-derived vesicle, releasing PLIN3/TIP47 in preparation for vesicle fusion (Espinosa et al, 2009; reviewed in Pfeffer, 2011).

Literature References
PubMed ID Title Journal Year
19490898 RhoBTB3: a Rho GTPase-family ATPase required for endosome to Golgi transport

Espinosa, EJ, Calero, M, Sridevi, K, Pfeffer, SR

Cell 2009
21421921 Entry at the trans-face of the Golgi

Pfeffer, SR

Cold Spring Harb Perspect Biol 2011
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
ATPase activity of RAB9:GTP:PLIN3:p-RABEPK:late-endosome-to-TGN cargo:VAMP3:RHOBTB3:ATP [transport vesicle]
Physical Entity
Activity
Orthologous Events
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