RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm]

Stable Identifier
R-HSA-6814534
Type
Complex
Species
Homo sapiens
Compartment
Synonyms
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:Pre-snRNA:RNU1-1,RNU2-1 gene:TBP:TFIIB:TFIIA:TFIIF:snTAFc:CDK7:SNAPc:POU2F1:ZNF143
Literature References
PubMed ID Title Journal Year
22137580 Ser7 phosphorylation of the CTD recruits the RPAP2 Ser5 phosphatase to snRNA genes

Egloff, S, Zaborowska, J, Laitem, C, Kiss, T, Murphy, S

Mol. Cell 2012
23932780 The little elongation complex functions at initiation and elongation phases of snRNA gene transcription

Hu, D, Smith, ER, Garruss, AS, Mohaghegh, N, Varberg, JM, Lin, C, Jackson, J, Gao, X, Saraf, A, Florens, LA, Washburn, MP, Eissenberg, JC, Shilatifard, A

Mol. Cell 2013
24997600 RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation

Ni, Z, Xu, C, Guo, X, Hunter, GO, Kuznetsova, OV, Tempel, W, Marcon, E, Zhong, G, Guo, H, Kuo, WH, Li, J, Young, P, Olsen, JB, Wan, C, Loppnau, P, El Bakkouri, M, Senisterra, GA, He, H, Huang, H, Sidhu, SS, Emili, A, Murphy, S, Mosley, AL, Arrowsmith, CH, Min, J, Greenblatt, JF

Nat. Struct. Mol. Biol. 2014
25675981 The Integrator complex controls the termination of transcription at diverse classes of gene targets

Skaar, JR, Ferris, AL, Wu, X, Saraf, A, Khanna, KK, Florens, LA, Washburn, MP, Hughes, SH, Pagano, M

Cell Res. 2015
22231121 Control of the RNA polymerase II phosphorylation state in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B

Ni, Z, Olsen, JB, Guo, X, Zhong, G, Ruan, ED, Marcon, E, Young, P, Guo, H, Li, J, Moffat, J, Emili, A, Greenblatt, JF

Transcription 2011
Participants
Participant Of
Inferred To