Reactome | KRTAP5-7 [cytosol]

KRTAP5-7 [cytosol]

Stable Identifier

R-HSA-6810273

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Keratin-associated protein 5-7, KRA57_HUMAN

Locations in the PathwayBrowser

Expand all

Developmental Biology (Homo sapiens)

- Keratinization (Homo sapiens)
  - Formation of hair keratin fibres (Homo sapiens)
    - Keratin associated proteins [cytosol] (Homo sapiens)
      - KRTAP5s [cytosol] (Homo sapiens)
        
        KRTAP5-7 [cytosol] (Homo sapiens)
    - Keratin tonofilament:Keratin associated proteins polymer [cytosol] (Homo sapiens)
      - Keratin tonofilament, KAPs [cytosol] (Homo sapiens)
        
        Keratin associated proteins [cytosol] (Homo sapiens)
        
        KRTAP5s [cytosol] (Homo sapiens)
        
        KRTAP5-7 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q6L8G8 KRTAP5-7

Gene Names

KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7

Chain

chain:1-165

Reference Genes

BioGPS Gene:440050 KRTAP5-7

COSMIC (genes):KRTAP5-7 KRTAP5-7

CTD Gene:440050 KRTAP5-7

dbSNP Gene:440050 KRTAP5-7

ENSEMBL:ENSG00000244411.4 KRTAP5-7

HGNC:23602 KRTAP5-7

KEGG Gene (Homo sapiens):440050 KRTAP5-7

Monarch:440050 KRTAP5-7

NCBI Gene:440050 KRTAP5-7

UCSC:Q6L8G8 KRTAP5-7

Reference Transcript

RefSeq:NM_001012503.1 KRTAP5-7

Other Identifiers

11734609_at

11734610_x_at

16728503

3316967

3316971

3316994

3339037

3339038

3339039

3339040

3339041

3339042

3339043

3339053

3358903

3358910

3358923

440050

7942255

8180254

8180382

A_14_P100710

A_33_P3228709

GE531378

GO:0005515

GO:0005622

GO:0005737

GO:0005829

GO:0005856

GO:0005882

GO:0043226

GO:0045095

HMNXSV003052219

ILMN_1791777

TC11000735.hg

g10567823_3p_s_at

Participates

as a member of

KRTAP5s [cytosol] (Homo sapiens)

Inferred To

Krtap5-2 [cytosol] (Mus musculus)

Gm29735 [cytosol] (Mus musculus)

Gm45618 [cytosol] (Mus musculus)

Krtap5-1 [cytosol] (Mus musculus)

Gm40460 [cytosol] (Mus musculus)

Gm10153 [cytosol] (Mus musculus)

Homologues of KRTAP5-7 [cytosol] (Mus musculus)

Homologues of KRTAP5-7 [cytosol] (Rattus norvegicus)

Homologues of KRTAP5-7 [cytosol] (Xenopus tropicalis)

Gm39115 [cytosol] (Mus musculus)

Gm45337 [cytosol] (Mus musculus)

Gm4559 [cytosol] (Mus musculus)

KRTAP5-7 [cytosol] (Canis familiaris)

KRTAP5-7 [cytosol] (Rattus norvegicus)

KRTAP5-7 [cytosol] (Sus scrofa)

KRTAP5-7 [cytosol] (Xenopus tropicalis)

Gm4553 [cytosol] (Mus musculus)

LOC685544 [cytosol] (Rattus norvegicus)

Gm7579 [cytosol] (Mus musculus)

Krtap5-4 [cytosol] (Mus musculus)

Krtap5-5 [cytosol] (Mus musculus)

Cross References

RefSeq

NP_001012521.1

OpenTargets

ENSG00000244411

GeneCards

Q6L8G8

HPA

ENSG00000244411-KRTAP5-7

Ensembl

ENST00000398536, ENSG00000244411, ENSP00000417330

PRO

Q6L8G8

Pharos - Targets

Q6L8G8

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q92608 DOCK2	3	DOCK2 [specific granule lumen] (R-HSA-6799558) DOCK2 [extracellular region] (R-HSA-6806310) DOCK2 [cytosol] (R-HSA-200938)	0.556	3
UniProt:Q49AN0 CRY2	4	p-S-CRY2 [cytosol] (R-HSA-400305) p-S-CRY2 [nucleoplasm] (R-HSA-400328) CRY2 [cytosol] (R-HSA-400255) Ub-p-S-CRY2 [nucleoplasm] (R-HSA-517935)	0.556	3
UniProt:P24592 IGFBP6	1	IGFBP6 [extracellular region] (R-HSA-381475)	0.556	3
UniProt:Q92504 SLC39A7	1	SLC39A7 [endoplasmic reticulum membrane] (R-HSA-442363)	0.556	3
UniProt:P31785 IL2RG	4	IL2RG [endosome] (R-HSA-8983165) p-Y-IL2RG [cytosol] (R-HSA-9009721) p-Y-IL2RG [plasma membrane] (R-HSA-6786103) IL2RG [plasma membrane] (R-HSA-449139)	0.556	3
UniProt:Q9UBK9 UXT	1	UXT [nucleoplasm] (R-HSA-9007484)	0.556	3
UniProt:Q8WUK0 PTPMT1	1	PTPMT1 [mitochondrial inner membrane] (R-HSA-3446802)	0.556	3
UniProt:Q14162 SCARF1	2	SCARF1 [plasma membrane] (R-HSA-2197636) SCARF1 [endocytic vesicle membrane] (R-HSA-2239453)	0.556	3

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