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Go!
MTMR8 [cytosol]
Stable Identifier
R-HSA-1604671
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
PI Metabolism (Homo sapiens)
Synthesis of PIPs at the plasma membrane (Homo sapiens)
MTMR8 binds MTMR9 (Homo sapiens)
MTMR8 [cytosol] (Homo sapiens)
MTMR8:MTMR9 [cytosol] (Homo sapiens)
MTMR8 [cytosol] (Homo sapiens)
PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Homo sapiens)
MTMR6:MTMR9,MTMR8:MTMR9 [cytosol] (Homo sapiens)
MTMR8:MTMR9 [cytosol] (Homo sapiens)
MTMR8 [cytosol] (Homo sapiens)
PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane (Homo sapiens)
MTMR6:MTMR9,MTMR8:MTMR9 [cytosol] (Homo sapiens)
MTMR8:MTMR9 [cytosol] (Homo sapiens)
MTMR8 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96EF0 MTMR8
Gene Names
MTMR8
Chain
chain:1-704
Reference Genes
BioGPS Gene:55613 MTMR8
COSMIC (genes):MTMR8 MTMR8
CTD Gene:55613 MTMR8
dbSNP Gene:55613 MTMR8
ENSEMBL:ENSG00000102043 MTMR8
ENSEMBL_homo_sapiens_GENE:ENSG00000102043.16 MTMR8
HGNC:16825 MTMR8
KEGG Gene (Homo sapiens):55613 MTMR8
Monarch:55613 MTMR8
NCBI Gene:55613 MTMR8
OMIM:301061 MTMR8
UCSC:Q96EF0 MTMR8
Reference Transcript
RefSeq:NM_017677.3 MTMR8
Other Identifiers
11755692_a_at
17111656
220537_PM_at
220537_at
221390_PM_s_at
221390_s_at
4010682
4010683
4010684
4010686
4010698
4010700
4010701
4010702
4010705
4010706
4010707
4010708
4010709
4010710
4010711
4010712
4010713
4010714
4010719
55613
68610_at
8173245
88512_at
A_23_P84995
GE577509
GO:0003824
GO:0004438
GO:0005515
GO:0005634
GO:0005635
GO:0005737
GO:0005829
GO:0006629
GO:0006914
GO:0010507
GO:0016241
GO:0016311
GO:0016787
GO:0016791
GO:0032991
GO:0043226
GO:0046488
GO:0046856
GO:0052629
GO:0106018
HMNXSV003043538
ILMN_1710652
ILMN_2160140
PH_hs_0025870
TC0X002333.hg
g10863890_3p_s_at
g8923125_3p_at
Participates
as a component of
MTMR8:MTMR9 [cytosol] (Homo sapiens)
as an input of
MTMR8 binds MTMR9 (Homo sapiens)
Inferred To
YMR1 [cytosol]
(Saccharomyces cerevisiae)
MTMR8 [cytosol]
(Bos taurus)
MTMR8 [cytosol]
(Caenorhabditis elegans)
MTMR8 [cytosol]
(Danio rerio)
MTMR8 [cytosol]
(Dictyostelium discoideum)
MTMR8 [cytosol]
(Drosophila melanogaster)
MTMR8 [cytosol]
(Gallus gallus)
MTMR8 [cytosol]
(Schizosaccharomyces pombe)
MTMR8 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_060147.2
OpenTargets
ENSG00000102043
IntEnz
3.1.3.64
GeneCards
Q96EF0
HPA
ENSG00000102043-MTMR8
Ensembl
ENSP00000363985
,
ENSG00000102043
,
ENST00000374852
PRO
Q96EF0
Pharos - Targets
Q96EF0
PDB
4Y7I
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96QG7 MTMR9
1
MTMR9 [cytosol]
(R-HSA-6809239)
0.853
8
UniProt:Q969Q4 ARL11
0.527
2
UniProt:Q9Y216 MTMR7
1
MTMR7 [cytosol]
(R-HSA-1604650)
0.527
2
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