Reactome | COG5 [Golgi membrane]

COG5 [Golgi membrane]

Stable Identifier

R-HSA-6808725

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Transport to the Golgi and subsequent modification (Homo sapiens)
      - ER to Golgi Anterograde Transport (Homo sapiens)
        
        COPI-mediated anterograde transport (Homo sapiens)
        
        COPI vesicle uncoating (Homo sapiens)
        
        COG complex [Golgi membrane] (Homo sapiens)
        
        COG5 [Golgi membrane] (Homo sapiens)
        
        RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Homo sapiens)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
        
        COG complex [Golgi membrane] (Homo sapiens)
        
        COG5 [Golgi membrane] (Homo sapiens)
        
        Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Homo sapiens)
        
        COG complex [Golgi membrane] (Homo sapiens)
        
        COG5 [Golgi membrane] (Homo sapiens)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
        
        COG complex [Golgi membrane] (Homo sapiens)
        
        COG5 [Golgi membrane] (Homo sapiens)
        
        cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Homo sapiens)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
        
        COG complex [Golgi membrane] (Homo sapiens)
        
        COG5 [Golgi membrane] (Homo sapiens)
        
        RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Homo sapiens)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
        
        COG complex [Golgi membrane] (Homo sapiens)
        
        COG5 [Golgi membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9UP83 COG5

Gene Names

COG5, GOLTC1, GTC90

Chain

chain:1-839

Reference Genes

BioGPS Gene:10466 COG5

COSMIC (genes):COG5 COG5

CTD Gene:10466 COG5

dbSNP Gene:10466 COG5

ENSEMBL:ENSG00000164597.15 COG5

HGNC:14857 COG5

KEGG Gene (Homo sapiens):10466 COG5

Monarch:10466 COG5

NCBI Gene:10466 COG5

OMIM:606821 COG5

UCSC:Q9UP83 COG5

Reference Transcript

Other Identifiers

0004760008

0006350242

10466

11742053_a_at

11743664_a_at

11746451_a_at

17061592

203629_PM_s_at

203629_s_at

203630_PM_s_at

203630_s_at

227089_PM_at

227089_at

3067087

3067088

3067089

3067090

3067091

3067092

3067094

3067095

3067096

3067097

3067098

3067099

3067100

3067101

3067102

3067109

3067110

3067111

3067112

3067115

3067116

3067117

3067126

3067127

3067131

3067140

3067143

3067144

3067145

3067148

3067156

3067157

3067177

3067182

3067184

3067186

3067188

3067191

3067192

3067193

3067198

34737_at

53353_at

8142143

A_21_P0000029

A_23_P134614

GE619718

GE81627

GO:0000139

GO:0000301

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005794

GO:0005829

GO:0006891

GO:0007030

GO:0008150

GO:0015031

GO:0016020

GO:0016192

GO:0017119

GO:0032588

GO:0032991

GO:0043226

GO:0048219

GO:0070085

HMNXSV003001034

HMNXSV003055907

Hs.10882.2.A1_3p_at

Hs.239631.0.S2_3p_a_at

ILMN_1698621

ILMN_1721535

ILMN_2399877

PH_hs_0012904

TC07001743.hg

g5453669_3p_a_at

Participates

as a component of

COG complex [Golgi membrane] (Homo sapiens)

Other forms of this molecule

COG5 [trans-Golgi network membrane]

Inferred To

Cog5 [Golgi membrane] (Mus musculus)

Cog5 [Golgi membrane] (Rattus norvegicus)

Ghost homologue of COG5 [Golgi membrane] (Schizosaccharomyces pombe)

cog5 [Golgi membrane] (Dictyostelium discoideum)

cog5 [Golgi membrane] (Xenopus tropicalis)

cogc-5 [Golgi membrane] (Caenorhabditis elegans)

fws [Golgi membrane] (Drosophila melanogaster)

COG5 [Golgi membrane] (Bos taurus)

COG5 [Golgi membrane] (Canis familiaris)

COG5 [Golgi membrane] (Danio rerio)

COG5 [Golgi membrane] (Gallus gallus)

COG5 [Golgi membrane] (Sus scrofa)

Cross References

RefSeq

NP_859422.2, NP_001154992.1, NP_006339.3

OpenTargets

ENSG00000164597

HPA

ENSG00000164597-COG5

GeneCards

Q9UP83

Ensembl

ENST00000347053, ENST00000393603, ENSG00000164597, ENSP00000377228, ENSP00000334703, ENSP00000297135, ENST00000297135

PRO

Q9UP83

Pharos - Targets

Q9UP83

Orphanet

20270

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