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COG5 [Golgi membrane]
Stable Identifier
R-HSA-6808725
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
COPI vesicle uncoating (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
COPI vesicle uncoating (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Intra-Golgi traffic (Homo sapiens)
Formation of cis-SNARE complex and membrane fusion in intra-Golgi retrograde traffic (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
COG complex:CUX1 dimer:GOLGA5 dimer:STX5:PalmC-YKT6:BET1L:GOSR1:intra-Golgi retrograde cargo [Golgi membrane] (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
The COG complex and CUX1 and GOLGA5 dimers contribute to intra-Golgi vesicle tethering (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
COG complex:CUX1 dimer:GOLGA5 dimer:STX5:PalmC-YKT6:BET1L:GOSR1:intra-Golgi retrograde cargo [Golgi membrane] (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
The COG complex binds RABs at the Golgi membrane (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
COG complex:RABs [Golgi membrane] (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
The COG tethering complex interacts with numerous SNAREs at the Golgi membrane (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
COG complex:Golgi snares [Golgi membrane] (Homo sapiens)
COG complex [Golgi membrane] (Homo sapiens)
COG5 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UP83 COG5
Gene Names
COG5, GOLTC1, GTC90
Chain
chain:1-839
Reference Genes
BioGPS Gene:10466 COG5
COSMIC (genes):COG5 COG5
CTD Gene:10466 COG5
dbSNP Gene:10466 COG5
ENSEMBL:ENSG00000164597 COG5
HGNC:14857 COG5
KEGG Gene (Homo sapiens):10466 COG5
Monarch:10466 COG5
NCBI Gene:10466 COG5
OMIM:606821 COG5
UCSC:Q9UP83 COG5
Reference Transcript
RefSeq:NM_181733.2 COG5
RefSeq:NM_006348.3 COG5
RefSeq:NM_001161520.1 COG5
Other Identifiers
0004760008
0006350242
10466
11742053_a_at
11743664_a_at
11746451_a_at
17061592
20300
203629_s_at
203630_s_at
227089_at
3067087
3067088
3067089
3067090
3067091
3067092
3067094
3067095
3067096
3067097
3067098
3067099
3067100
3067101
3067102
3067109
3067110
3067111
3067112
3067115
3067116
3067117
3067126
3067127
3067131
3067140
3067143
3067144
3067145
3067148
3067156
3067157
3067177
3067182
3067184
3067186
3067188
3067191
3067192
3067193
34737_at
41583
53353_at
8142143
A_21_P0000029
A_23_P134614
AAB63816
AAC69276
AAC83406
AAH68540
AC002381
AC004855
AF058718
BC068540
CCDS55152
CCDS5742
CCDS5743
CH236947
CH471070
COG5
COG5-201
COG5-202
COG5-203
EAL24392
EAL24393
EAW83395
EAW83396
ENSG00000164597
ENSP00000297135
ENSP00000334703
ENSP00000377228
ENST00000297135
ENST00000297135.7
ENST00000347053
ENST00000347053.7
ENST00000393603
ENST00000393603.6
EntrezGene:10466
EntrezGene:COG5
g5453669_3p_a_at
GE619718
GE81627
GO:0000139
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005794
GO:0005829
GO:0006810
GO:0006888
GO:0006891
GO:0008150
GO:0015031
GO:0016020
GO:0016192
GO:0017119
GO:0032588
GO:0032991
GO:0043226
HGNC:14857
HPA020300
HPA041583
Hs.10882.2.A1_3p_at
Hs.239631.0.S2_3p_a_at
ILMN_1698621
ILMN_1721535
ILMN_2399877
IPR019465
MIM:606821
MIM:613612
NM_001161520
NM_006348
NM_181733
NP_001154992
NP_006339
NP_859422
PF10392
PH_hs_0012904
TC07001743.hg
U3KQU7
UPI000013E3CB
UPI0000246D05
UPI0000EE4017
XM_024446634
XP_024302402
Participant Of
hasComponent
COG complex [Golgi membrane]
Other forms of this molecule
COG5 [trans-Golgi network membrane]
Inferred To
Ghost homologue of COG5 [Golgi membrane] (Bos taurus)
COG5 [Golgi membrane] (Caenorhabditis elegans)
COG5 [Golgi membrane] (Canis familiaris)
COG5 [Golgi membrane] (Danio rerio)
COG5 [Golgi membrane] (Dictyostelium discoideum)
COG5 [Golgi membrane] (Drosophila melanogaster)
COG5 [Golgi membrane] (Gallus gallus)
COG5 [Golgi membrane] (Mus musculus)
COG5 [Golgi membrane] (Rattus norvegicus)
COG5 [Golgi membrane] (Schizosaccharomyces pombe)
COG5 [Golgi membrane] (Sus scrofa)
COG5 [Golgi membrane] (Xenopus tropicalis)
Cross References
RefSeq
NP_859422.2
,
NP_006339.3
,
NP_001154992.1
OpenTargets
ENSG00000164597
GeneCards
Q9UP83
PRO
Q9UP83
Orphanet
20270
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