Reactome | BSG [plasma membrane]

BSG [plasma membrane]

Stable Identifier

R-HSA-197673

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

CD147, Basigin precursor, BASI_HUMAN, Extracellular matrix metalloproteinase inducer, EMMPRIN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P35613 BSG

Gene Names

BSG, UNQ6505/PRO21383

Chain

signal peptide:1-21, chain:22-385

Reference Genes

BioGPS Gene:682 BSG

COSMIC (genes):BSG BSG

CTD Gene:682 BSG

dbSNP Gene:682 BSG

ENSEMBL:ENSG00000172270 BSG

HGNC:1116 BSG

KEGG:hsa:682 BSG

Monarch:682 BSG

NCBI Gene:682 BSG

OMIM:109480 BSG

UCSC:P35613 BSG

Reference Transcript

Other Identifiers

11735705_s_at

11735706_a_at

11739875_a_at

11739876_s_at

11739877_x_at

11754083_a_at

16856203

208677_PM_s_at

208677_s_at

36162_at

3815015

3815016

3815017

3815018

3815021

3815022

3815023

3815024

3815025

3815026

3815027

3815028

3815029

3815030

3815031

3815032

3815033

3815034

3815035

3815036

3815037

3815038

682

8023955

88316_at

A_14_P111762

A_24_P134266

A_24_P202769

GE62772

GO:0000139

GO:0001525

GO:0001618

GO:0001750

GO:0001917

GO:0002080

GO:0002376

GO:0003407

GO:0005515

GO:0005537

GO:0005739

GO:0005768

GO:0005783

GO:0005789

GO:0005886

GO:0005925

GO:0007166

GO:0007566

GO:0010575

GO:0010595

GO:0016020

GO:0016323

GO:0016328

GO:0022414

GO:0030593

GO:0031410

GO:0032755

GO:0038023

GO:0042383

GO:0042470

GO:0042475

GO:0042995

GO:0043226

GO:0043231

GO:0043434

GO:0045296

GO:0045494

GO:0046598

GO:0046689

GO:0046697

GO:0046718

GO:0048856

GO:0048870

GO:0051591

GO:0060089

GO:0061154

GO:0070062

GO:0072659

GO:1904466

HMNXSV003057612

Hs.74631.0.A1_3p_a_at

ILMN_1730709

ILMN_1778374

PH_hs_0030574

PH_hs_0032933

TC19000009.hg

X64364_at

Participates

as a component of

as an input of

Other forms of this molecule

BSG [Golgi membrane]

Inferred To

bsg [plasma membrane] (Xenopus tropicalis)

Bsg [plasma membrane] (Drosophila melanogaster)

Bsg [plasma membrane] (Mus musculus)

Bsg [plasma membrane] (Rattus norvegicus)

BSG [plasma membrane] (Bos taurus)

BSG [plasma membrane] (Canis familiaris)

BSG [plasma membrane] (Gallus gallus)

BSG [plasma membrane] (Sus scrofa)

rig-6 [plasma membrane] (Caenorhabditis elegans)

Cross References

RefSeq

NP_940993.1, NP_001719.2, NP_940992.1, NP_940991.1, XP_016882662.1, NP_001309172.1

OpenTargets

ENSG00000172270

ENSEMBL

ENSP00000473664, ENST00000353555, ENSP00000473393, ENST00000545507, ENST00000333511, ENSP00000344707, ENSP00000506020, ENSP00000343809, ENST00000346916, ENSP00000473528, ENST00000573784, ENST00000576984, ENST00000680065, ENSP00000333769

HPA

ENSG00000172270-BSG

PRO

P35613

Pharos - Targets

P35613

GlyGen

P35613

PDB

7DA5, 3B5H, 4U0Q, 7XY8, 7CKO, 5XF0, 6LZ0, 3I84, 7DAA, 7DCE, 7CKR, 3I85, 5X0T, 8XEJ, 6LYY, 3QQN, 3QR2

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC2 S	20	S(686-815) [plasma membrane] (R-COV-9770188) Spike S2' Fragment [plasma membrane] (R-COV-9770189) S1 [plasma membrane] (R-COV-9769950) fully glycosylated Spike [plasma membrane] (R-COV-9733472) nascent Spike [endoplasmic reticulum lumen] (R-COV-9694796) 14-sugar N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9694459) Man(9) N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696892) high-mannose N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696875) high-mannose N-glycan folded Spike [endoplasmic reticulum lumen] (R-COV-9696880) high-mannose N-glycan folded Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9766369) high-mannose N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696943) di-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696920) complex N-glycan-PALM-Spike S1 Fragment [virion membrane] (R-COV-9694638) complex N-glycan-PALM-Spike S2 Fragment [virion membrane] (R-COV-9694791) complex N-glycan-PALM-Spike S2 Fragment [endocytic vesicle membrane] (R-COV-9694343) complex N-glycan-PALM-Spike S1 Fragment [endocytic vesicle membrane] (R-COV-9694745) fully glycosylated Spike [virion membrane] (R-COV-9698327) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9698330) complex N-glycan-PALM-Spike S2 Fragment [plasma membrane] (R-COV-9769952) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696997)	0.652	7
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.615	12
UniProt:Q92542 NCSTN	3	NCSTN [plasma membrane] (R-HSA-2534241) NCSTN [azurophil granule membrane] (R-HSA-6799220) NCSTN [endosome membrane] (R-HSA-9010085)	0.591	6
UniProt:P49768-PRO_0000025592 PSEN1			0.591	6
UniProt:P62937 PPIA	5	PPIA [extracellular exosome] (R-HSA-6801538) PPIA [ficolin-1-rich granule lumen] (R-HSA-6801391) PPIA [extracellular region] (R-HSA-173646) PPIA [secretory granule lumen] (R-HSA-6801400) PPIA [cytosol] (R-HSA-173123)	0.589	2
UniProt:P27824 CANX	2	CANX [endoplasmic reticulum lumen] (R-HSA-195906) CANX [lumenal side of endoplasmic reticulum membrane] (R-HSA-983091)	0.569	4
UniProt:P20020 ATP2B1	1	ATP2B1 [plasma membrane] (R-HSA-418301)	0.527	2
UniProt:Q8NCK7 MOT11			0.499	5
UniProt:Q9UJC3 HOOK1			0.463	3

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