Reactome | CYB5R2 [endoplasmic reticulum membrane]

CYB5R2 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-6806861

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

NADH-cytochrome b5 reductase 2, NB5R2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q6BCY4 CYB5R2

Gene Names

CYB5R2

Chain

chain:1-276

Reference Genes

BioGPS Gene:51700 CYB5R2

COSMIC (genes):CYB5R2 CYB5R2

CTD Gene:51700 CYB5R2

dbSNP Gene:51700 CYB5R2

ENSEMBL:ENSG00000166394 CYB5R2

ENSEMBL_homo_sapiens_GENE:ENSG00000166394.15 CYB5R2

HGNC:24376 CYB5R2

KEGG Gene (Homo sapiens):51700 CYB5R2

Monarch:51700 CYB5R2

NCBI Gene:51700 CYB5R2

OMIM:608342 CYB5R2

UCSC:Q6BCY4 CYB5R2

Reference Transcript

Other Identifiers

11757682_a_at

16735259

220230_PM_s_at

220230_s_at

3361380

3361382

3361383

3361384

3361385

3361387

3361391

3361392

3361393

3361394

3361396

3361399

3361400

3361401

3361406

3361407

3361408

3361409

3361410

3361411

51700

56291_at

7946292

A_33_P3381265

GE58708

GO:0003824

GO:0004128

GO:0005515

GO:0005634

GO:0005739

GO:0005783

GO:0005789

GO:0006629

GO:0006694

GO:0008202

GO:0015701

GO:0016020

GO:0016126

GO:0016491

GO:0043226

GO:0071949

HMNXSV003045817

ILMN_1682407

ILMN_1739576

PH_hs_0019595

TC11001372.hg

g7706442_3p_a_at

Participates

as a member of

CYB5Rs [endoplasmic reticulum membrane] (Homo sapiens)

Inferred To

CYB5R2 [endoplasmic reticulum membrane] (Bos taurus)

CYB5R2 [endoplasmic reticulum membrane] (Canis familiaris)

CYB5R2 [endoplasmic reticulum membrane] (Danio rerio)

CYB5R2 [endoplasmic reticulum membrane] (Gallus gallus)

CYB5R2 [endoplasmic reticulum membrane] (Mus musculus)

CYB5R2 [endoplasmic reticulum membrane] (Rattus norvegicus)

CYB5R2 [endoplasmic reticulum membrane] (Xenopus tropicalis)

Cross References

RefSeq

XP_011518486.1, NP_057313.2, NP_001289755.1, XP_005253032.1, XP_006718314.1

OpenTargets

ENSG00000166394

GeneCards

Q6BCY4

HPA

ENSG00000166394-CYB5R2

Ensembl

ENSP00000299498, ENST00000524790, ENST00000299498, ENSP00000437041, ENSG00000166394, ENST00000533558, ENSP00000435916

PRO

Q6BCY4

Pharos - Targets

Q6BCY4

HMDB Protein

HMDBP07264

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3
UniProt:Q13077 TRAF1	3	TRAF1 [cytosol] (R-HSA-5634163) TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.556	3
UniProt:P62333 PSMC6	2	PSMC6 [nucleoplasm] (R-HSA-174319) PSMC6 [cytosol] (R-HSA-68783)	0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [nucleoplasm] (R-HSA-8862199) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) TRAF2 [cytosol] (R-HSA-66370)	0.556	3

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