TP53 binds STK11 and NUAK1

Stable Identifier
R-HSA-6805035
Type
Reaction
Species
Homo sapiens
Compartment
nucleoplasm
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TP53 binds STK11 and NUAK1
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In the presence of STK11 (LTKB1), TP53 associates with NUAK1 (Zeng and Berger 2006, Hou et al. 2011).

Literature References
PubMed ID Title Journal Year
21317932 A new role of NUAK1: directly phosphorylating p53 and regulating cell proliferation

Liu, JE, Liu, ZY, Liu, W, Sun, ZY, Liu, CY, Hou, X

Oncogene 2011
17108107 LKB1 is recruited to the p21/WAF1 promoter by p53 to mediate transcriptional activation

Zeng, PY, Berger, SL

Cancer Res. 2006
Participants
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Output
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Orthologous Events
TP53 binds STK11 and NUAK1 (Bos taurus)
TP53 binds STK11 and NUAK1 (Mus musculus)
TP53 binds STK11 and NUAK1 (Rattus norvegicus)
TP53 binds STK11 and NUAK1 (Sus scrofa)
Authored
Orlic-Milacic, M  (2015-10-14)
Reviewed
Zaccara, S  (2016-02-04)
Inga, A  (2016-02-04)
Created
Orlic-Milacic, M  (2015-10-16)
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