Reactome | PLAGL1 [nucleoplasm]

PLAGL1 [nucleoplasm]

Stable Identifier

R-HSA-6803945

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Zinc finger protein PLAGL1, ZAC1, ZAC-1, ZAC, LOT-1, LOT1, Pleiomorphic adenoma-like protein 1, Lost on transformation 1, Tumor suppressor ZAC

Locations in the PathwayBrowser for interactor UniProt:Q63ZY3 KANK2

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional Regulation by TP53 (Homo sapiens)
      - TP53 Regulates Transcription of Cell Cycle Genes (Homo sapiens)
        
        TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Homo sapiens)
        
        TP53 stimulates PLAGL1 expression (Homo sapiens)
        
        PLAGL1 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9UM63 PLAGL1

Gene Names

PLAGL1, LOT1, ZAC

Chain

chain:1-463

Reference Genes

BioGPS Gene:5325 PLAGL1

COSMIC - genes:PLAGL1 PLAGL1

CTD Gene:5325 PLAGL1

dbSNP Gene:5325 PLAGL1

ENSEMBL:ENSG00000118495 PLAGL1

HGNC:9046 PLAGL1

KEGG:hsa:5325 PLAGL1

Monarch:5325 PLAGL1

NCBI Gene:5325 PLAGL1

OMIM:603044 PLAGL1

UCSC:Q9UM63 PLAGL1

Reference Transcript

Other Identifiers

11734150_x_at

11737052_x_at

11741152_x_at

11745820_s_at

11745821_a_at

17024394

207002_PM_s_at

207002_s_at

207943_PM_x_at

207943_x_at

209318_PM_x_at

209318_x_at

2977622

2977623

2977624

2977625

2977626

2977627

2977628

2977630

2977631

2977632

2977633

2977634

2977635

2977636

2977637

2977638

2977639

2977640

2977647

2977648

2977650

2977651

2977652

2977653

2977654

2977655

2977656

2977657

2977658

2977659

2977660

2977661

2977662

2977663

2977669

2977680

2977681

2977684

36943_r_at

36944_f_at

5325

57266_r_at

8129985

86256_at

A_23_P8175

A_24_P312041

GE81174

GE847759

GO:0000122

GO:0000977

GO:0000978

GO:0001227

GO:0001228

GO:0001817

GO:0002682

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005794

GO:0006355

GO:0006357

GO:0006915

GO:0008270

GO:0016604

GO:0043565

GO:0045944

GO:0046872

GO:0051726

HMNXSV003033536

HMNXSV003036205

Hs.75825.2.S1_3p_a_at

ILMN_1711098

ILMN_1815121

ILMN_2356955

PH_hs_0027835

PH_hs_0041149

TC06002189.hg

TC06003906.hg

U72621_at

g4505856_3p_x_at

p33888

Participates

as an output of

TP53 stimulates PLAGL1 expression (Homo sapiens)

Cross References

RefSeq

NP_006709.2, NP_001074424.1, NP_001275978.1, NP_001275977.1, NP_001275970.1, NP_001074425.1, NP_001275968.1, NP_001275967.1, NP_001304089.1, NP_001275969.1, NP_001304088.1, NP_001275966.1, NP_001074423.1, NP_001074422.1, NP_001275976.1, NP_001304091.1, NP_001275975.1, NP_001275971.1, NP_001275972.1, NP_001304090.1, NP_001275973.1, NP_001304087.1, NP_001074421.1, NP_001304086.1, NP_001304085.1, NP_001275974.1, NP_001074420.1

OpenTargets

ENSG00000118495

ENSEMBL

ENST00000417959, ENSP00000501459, ENST00000647880, ENSP00000496815, ENSP00000496979, ENSG00000118495, ENSP00000497492, ENSP00000486355, ENST00000416623, ENST00000360537, ENST00000367572, ENST00000367571, ENSP00000395960, ENSP00000400929, ENSP00000346810, ENST00000444202, ENST00000650125, ENSP00000356544, ENST00000674357, ENSP00000356543, ENST00000354765, ENST00000437412, ENST00000625622, ENSP00000497363, ENSP00000353734, ENSP00000392418, ENST00000649307, ENSP00000400060, ENST00000649211

HPA

ENSG00000118495-PLAGL1

GeneCards

PLAGL1

PRO

Q9UM63

Pharos - Targets

Q9UM63

Orphanet

PLAGL1

HMDB Protein

HMDBP14049

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q63ZY3 KANK2			0.556	3
UniProt:Q08117-2 TLE5			0.556	3