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DOK3 [secretory granule membrane]
Stable Identifier
R-HSA-6801402
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
secretory granule membrane
Synonyms
Docking protein 3, DOK3_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of secretory granule membrane proteins (Homo sapiens)
Secretory granule membrane proteins [secretory granule membrane] (Homo sapiens)
DOK3 [secretory granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7L591 DOK3
Gene Names
DOK3
Chain
chain:1-496
Reference Genes
BioGPS Gene:79930 DOK3
COSMIC (genes):DOK3 DOK3
CTD Gene:79930 DOK3
dbSNP Gene:79930 DOK3
ENSEMBL:ENSG00000146094 DOK3
ENSEMBL_homo_sapiens_GENE:ENSG00000146094.16 DOK3
HGNC:24583 DOK3
KEGG Gene (Homo sapiens):79930 DOK3
Monarch:79930 DOK3
NCBI Gene:79930 DOK3
OMIM:611435 DOK3
UCSC:Q7L591 DOK3
Reference Transcript
RefSeq:NM_024872.2 DOK3
RefSeq:NM_001144876.1 DOK3
RefSeq:NM_001308235.1 DOK3
RefSeq:NM_001144875.1 DOK3
RefSeq:XM_005265987.1 DOK3
RefSeq:NM_001308236.1 DOK3
Other Identifiers
11726473_a_at
223553_PM_s_at
223553_s_at
2888880
2888881
2888885
2888886
2888887
2888890
2888891
2888894
2888895
2888896
2888903
2889021
2889127
2889128
2889129
2889131
2889134
2889135
2889136
2889141
73705_at
79930
8116086
A_32_P121085
A_33_P3228564
GE85514
GO:0005515
GO:0005737
GO:0005886
GO:0007169
GO:0007265
GO:0016020
GO:0023052
GO:0030667
GO:0031410
GO:0043226
GO:0043410
GO:0101003
HMNXSV003022111
g13528734_3p_a_at
Participates
as a member of
Secretory granule membrane proteins [secretory granule membrane] (Homo sapiens)
Other forms of this molecule
DOK3 [ficolin-1-rich granule membrane]
DOK3 [plasma membrane]
Inferred To
DOK3 [secretory granule membrane]
(Bos taurus)
DOK3 [secretory granule membrane]
(Canis familiaris)
DOK3 [secretory granule membrane]
(Gallus gallus)
DOK3 [secretory granule membrane]
(Sus scrofa)
Dok3 [secretory granule membrane]
(Mus musculus)
Dok3 [secretory granule membrane]
(Rattus norvegicus)
Dok [secretory granule membrane]
(Drosophila melanogaster)
rog-1 [secretory granule membrane]
(Caenorhabditis elegans)
dok2 [secretory granule membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001138348.1
,
NP_001295164.1
,
NP_079148.2
,
XP_005266044.1
,
NP_001138347.1
,
NP_001295165.1
OpenTargets
ENSG00000146094
HPA
ENSG00000146094-DOK3
GeneCards
Q7L591
Ensembl
ENSP00000366316
,
ENSP00000325174
,
ENST00000377112
,
ENST00000312943
,
ENSG00000146094
PRO
Q7L591
Pharos - Targets
Q7L591
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13077 TRAF1
3
TRAF1 [cytosol]
(R-HSA-5634163)
TRAF1(1-163) [cytosol]
(R-HSA-5634199)
TRAF1(164-416) [cytosol]
(R-HSA-5634204)
0.666
4
UniProt:P00533 EGFR
20
p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869138)
p-5Y-EGFRvIII [plasma membrane]
(R-HSA-1248649)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
p-6Y-EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1182985)
p-6Y-EGFR L858R;T790M [plasma membrane]
(R-HSA-1182984)
p-6Y-EGFR A767_V769dup [plasma membrane]
(R-HSA-1996343)
p-6Y-EGFR N771_H773dup [plasma membrane]
(R-HSA-1996342)
p-6Y-EGFR K739_I744dup [plasma membrane]
(R-HSA-1996346)
p-6Y-EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996335)
p-6Y-EGFR E746_A750del [plasma membrane]
(R-HSA-1181214)
p-6Y-EGFR L858R [plasma membrane]
(R-HSA-1173211)
p-6Y-EGFR G719S [plasma membrane]
(R-HSA-1169417)
p-6Y-EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228038)
p-6Y-EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228044)
p-6Y-EGFR L747_T751del [plasma membrane]
(R-HSA-1228041)
p-6Y-EGFR L747_S752del [plasma membrane]
(R-HSA-1228040)
p-6Y-EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228042)
p-6Y-EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228037)
p-6Y-EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228039)
p-6Y-EGFR L861Q [plasma membrane]
(R-HSA-1177541)
0.508
2
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