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CHIT1 [tertiary granule lumen]
Stable Identifier
R-HSA-6800898
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
tertiary granule lumen
Synonyms
Chitotriosidase-1 ecNumber3.2.1.14/ecNumber, CHIT1_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of tertiary granule lumen proteins (Homo sapiens)
Tertiary granule lumen proteins [tertiary granule lumen] (Homo sapiens)
CHIT1 [tertiary granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13231 CHIT1
Gene Names
CHIT1
Chain
signal peptide:1-21, chain:22-466
Reference Genes
BioGPS Gene:1118 CHIT1
COSMIC (genes):CHIT1 CHIT1
CTD Gene:1118 CHIT1
dbSNP Gene:1118 CHIT1
ENSEMBL:ENSG00000133063 CHIT1
HGNC:1936 CHIT1
KEGG:hsa:1118 CHIT1
Monarch:1118 CHIT1
NCBI Gene:1118 CHIT1
OMIM:600031 CHIT1
UCSC:Q13231 CHIT1
Reference Transcript
RefSeq:NM_001256125.1 CHIT1
RefSeq:NM_003465.2 CHIT1
Other Identifiers
1118
11756970_a_at
16698200
208168_PM_s_at
208168_s_at
2451617
2451618
2451619
2451620
2451621
2451622
2451623
2451624
2451625
2451626
2451627
2451628
2451629
2451630
2451631
2451632
2451636
2451638
2451639
2451640
2451642
2451643
2451644
2451649
2451650
2451651
2451652
2451653
37061_at
7923562
A_23_P126278
A_33_P3388501
A_33_P3411333
GE61928
GE852216
GO:0000272
GO:0002376
GO:0003824
GO:0004553
GO:0004568
GO:0005515
GO:0005576
GO:0005615
GO:0005764
GO:0005773
GO:0005975
GO:0006032
GO:0006955
GO:0008061
GO:0008843
GO:0009617
GO:0016787
GO:0016798
GO:0035580
GO:0043226
GO:0044245
GO:1901135
GO:1904724
HMNXSV003046926
HMNXSV003055166
PH_hs_0022990
PH_hs_0032147
U29615_at
g4502808_3p_a_at
Participates
as a member of
Tertiary granule lumen proteins [tertiary granule lumen] (Homo sapiens)
Other forms of this molecule
CHIT1 [specific granule lumen]
CHIT1 [extracellular region]
Inferred To
chia.3 [tertiary granule lumen]
(Danio rerio)
CHIT1 [tertiary granule lumen]
(Caenorhabditis elegans)
CHIT1 [tertiary granule lumen]
(Mus musculus)
CHIT1 [tertiary granule lumen]
(Sus scrofa)
Chit1 [tertiary granule lumen]
(Rattus norvegicus)
chia.2 [tertiary granule lumen]
(Danio rerio)
Homologues of CHIT1 [tertiary granule lumen]
(Danio rerio)
CHT1 [tertiary granule lumen]
(Plasmodium falciparum)
Cht11 [tertiary granule lumen]
(Drosophila melanogaster)
CTS2 [tertiary granule lumen]
(Saccharomyces cerevisiae)
Cross References
Guide to Pharmacology - Targets
3187
OpenTargets
ENSG00000133063
ENSEMBL
ENST00000367229
,
ENSP00000255427
,
ENST00000491855
,
ENSP00000356198
,
ENST00000255427
,
ENSP00000423778
IntEnz
3.2.1.14
HPA
ENSG00000133063-CHIT1
ZINC - Substances
CHIT1_HUMAN
ZINC target
Q13231
PRO
Q13231
Pharos - Targets
Q13231
HMDB Protein
HMDBP01031
PDB
5NRF
,
4WKF
,
6JJR
,
1LG2
,
1HKK
,
1HKJ
,
1GUV
,
1LG1
,
1HKI
,
1WB0
,
4WK9
,
4WJX
,
4WKA
,
5NRA
,
4WKH
,
1WAW
,
1HKM
,
1LQ0
,
5NR8
,
5HBF
,
6JK6
,
6SO0
,
6ZE8
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P43353 ALDH3B1
3
ALDH3B1 [secretory granule membrane]
(R-HSA-6801023)
ALDH3B1 [plasma membrane]
(R-HSA-5696096)
ALDH3B1 [specific granule membrane]
(R-HSA-6799510)
0.527
2
UniProt:Q96DB5 RMD1
0.527
2
UniProt:P40337 VHL
3
monoSUMO1-K159,171,196-VHL [nucleoplasm]
(R-HSA-4551697)
VHL [nucleoplasm]
(R-HSA-1234127)
VHL [cytosol]
(R-HSA-391423)
0.499
2
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