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LAIR1 [specific granule membrane]
Stable Identifier
R-HSA-6799644
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
specific granule membrane
Synonyms
Leukocyte-associated immunoglobulin-like receptor 1, LAIR1_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of specific granule membrane proteins (Homo sapiens)
Specific granule membrane proteins [specific granule membrane] (Homo sapiens)
LAIR1 [specific granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6GTX8 LAIR1
Gene Names
LAIR1, CD305
Chain
signal peptide:1-21, chain:22-287
Reference Genes
BioGPS Gene:3903 LAIR1
COSMIC (genes):LAIR1 LAIR1
CTD Gene:3903 LAIR1
dbSNP Gene:3903 LAIR1
ENSEMBL:ENSG00000167613 LAIR1
ENSEMBL_homo_sapiens_GENE:ENSG00000167613.16 LAIR1
ENSEMBL_homo_sapiens_GENE:ENSG00000274110.4 LAIR1
ENSEMBL_homo_sapiens_GENE:ENSG00000276053.4 LAIR1
ENSEMBL_homo_sapiens_GENE:ENSG00000276163.4 LAIR1
ENSEMBL_homo_sapiens_GENE:ENSG00000278154.4 LAIR1
HGNC:6477 LAIR1
KEGG Gene (Homo sapiens):3903 LAIR1
Monarch:3903 LAIR1
NCBI Gene:3903 LAIR1
OMIM:602992 LAIR1
UCSC:Q6GTX8 LAIR1
Reference Transcript
RefSeq:NM_021706.4 LAIR1
RefSeq:NM_002287.5 LAIR1
RefSeq:NM_001289025.2 LAIR1
RefSeq:NM_001289023.2 LAIR1
Other Identifiers
11724804_x_at
11724805_a_at
11748339_a_at
11748340_x_at
208071_PM_s_at
208071_s_at
210644_PM_s_at
210644_s_at
37470_at
3841509
3841511
3870820
3870822
3870823
3870825
3870826
3870827
3870828
3870829
3870831
3870832
3870835
3870840
3870842
3870843
3870846
3870848
3870849
3903
8039257
90514_at
A_23_P209135
A_24_P262688
A_33_P3253394
A_33_P3355230
GE54119
GE844549
GO:0002250
GO:0002376
GO:0005515
GO:0005886
GO:0016020
GO:0031410
GO:0035579
GO:0043226
GO:0070821
HMNXSV003018760
HMNXSV003020504
ILMN_1768598
ILMN_2389211
PH_hs_0019448
PH_hs_0021375
TC19001844.hg
g11231178_3p_a_at
g6563041_3p_a_at
p8451
Participates
as a member of
Specific granule membrane proteins [specific granule membrane] (Homo sapiens)
Other forms of this molecule
LAIR1 [plasma membrane]
LAIR1 [tertiary granule membrane]
Inferred To
Homologues of FCAR [specific granule membrane]
(Xenopus tropicalis)
Lair1 [specific granule membrane]
(Mus musculus)
Lair1 [specific granule membrane]
(Rattus norvegicus)
FCAR [specific granule membrane]
(Xenopus tropicalis)
Homologues of LAIR1 [specific granule membrane]
(Sus scrofa)
LOC100515837 [specific granule membrane]
(Sus scrofa)
LAIR1 [specific granule membrane]
(Bos taurus)
LAIR1 [specific granule membrane]
(Canis familiaris)
LAIR1 [specific granule membrane]
(Sus scrofa)
Cross References
RefSeq
NP_001275954.2
,
NP_002278.2
,
NP_068352.2
,
NP_001275952.2
Guide to Pharmacology - Targets
2974
OpenTargets
ENSG00000167613
GeneCards
Q6GTX8
HPA
ENSG00000167613-LAIR1
Ensembl
ENSP00000482922
,
ENSP00000479133
,
ENST00000614937
,
ENST00000622097
,
ENST00000620357
,
ENSP00000478853
,
ENSG00000278154
,
ENSP00000418998
,
ENST00000616612
,
ENSP00000375622
,
ENSG00000276053
,
ENSG00000274110
,
ENST00000614946
,
ENST00000619717
,
ENST00000619817
,
ENST00000348231
,
ENST00000610549
,
ENSP00000479682
,
ENSP00000479707
,
ENSP00000480619
,
ENSP00000301193
,
ENST00000620726
,
ENSP00000481204
,
ENSP00000480659
,
ENSP00000479006
,
ENSP00000478405
,
ENSG00000167613
,
ENST00000474878
,
ENST00000620077
,
ENST00000618434
,
ENSG00000276163
,
ENSP00000479649
,
ENST00000391742
PRO
Q6GTX8
Pharos - Targets
Q6GTX8
HMDB Protein
HMDBP07769
PDB
3RP1
,
3KGR
,
7F9M
,
7F9L
,
7F9N
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P29350 PTPN6
5
PTPN6 [tertiary granule lumen]
(R-HSA-6800952)
PTPN6 [extracellular region]
(R-HSA-6806315)
PTPN6 [specific granule lumen]
(R-HSA-6799641)
PTPN6 [nucleoplasm]
(R-HSA-9008911)
PTPN6 [cytosol]
(R-HSA-197938)
0.613
5
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