Reactome | LAIR1 [specific granule membrane]

LAIR1 [specific granule membrane]

Stable Identifier

R-HSA-6799644

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

specific granule membrane

Synonyms

Leukocyte-associated immunoglobulin-like receptor 1, LAIR1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q6GTX8 LAIR1

Gene Names

LAIR1, CD305

Chain

signal peptide:1-21, chain:22-287

Reference Genes

BioGPS Gene:3903 LAIR1

COSMIC (genes):LAIR1 LAIR1

CTD Gene:3903 LAIR1

dbSNP Gene:3903 LAIR1

ENSEMBL:ENSG00000167613 LAIR1

ENSEMBL:ENSG00000167613.16 LAIR1

ENSEMBL:ENSG00000274110.4 LAIR1

ENSEMBL:ENSG00000276053.4 LAIR1

ENSEMBL:ENSG00000276163.4 LAIR1

ENSEMBL:ENSG00000278154.4 LAIR1

HGNC:6477 LAIR1

KEGG Gene (Homo sapiens):3903 LAIR1

Monarch:3903 LAIR1

NCBI Gene:3903 LAIR1

OMIM:602992 LAIR1

UCSC:Q6GTX8 LAIR1

Reference Transcript

Other Identifiers

11724804_x_at

11724805_a_at

11748339_a_at

11748340_x_at

208071_PM_s_at

208071_s_at

210644_PM_s_at

210644_s_at

37470_at

3841509

3841511

3870820

3870822

3870823

3870825

3870826

3870827

3870828

3870829

3870831

3870832

3870835

3870840

3870842

3870843

3870846

3870848

3870849

3903

8039257

90514_at

A_23_P209135

A_24_P262688

A_33_P3253394

A_33_P3355230

GE54119

GE844549

GO:0002250

GO:0002376

GO:0005515

GO:0005886

GO:0016020

GO:0031410

GO:0035579

GO:0043226

GO:0070821

HMNXSV003018760

HMNXSV003020504

ILMN_1768598

ILMN_2389211

PH_hs_0019448

PH_hs_0021375

TC19001844.hg

g11231178_3p_a_at

g6563041_3p_a_at

p8451

Participates

as a member of

Specific granule membrane proteins [specific granule membrane] (Homo sapiens)

Other forms of this molecule

LAIR1 [tertiary granule membrane]

LAIR1 [plasma membrane]

Inferred To

Homologues of FCAR [specific granule membrane] (Xenopus tropicalis)

Lair1 [specific granule membrane] (Mus musculus)

Lair1 [specific granule membrane] (Rattus norvegicus)

xilr1 [specific granule membrane] (Xenopus tropicalis)

LOC100515837 [specific granule membrane] (Sus scrofa)

xilr2 [specific granule membrane] (Xenopus tropicalis)

LAIR1 [specific granule membrane] (Bos taurus)

Cross References

RefSeq

NP_001275952.2, NP_068352.2, NP_002278.2, NP_001275954.2

Guide to Pharmacology - Targets

2974

OpenTargets

ENSG00000167613

HPA

ENSG00000167613-LAIR1

GeneCards

Q6GTX8

Ensembl

ENST00000391742, ENST00000619717, ENST00000619817, ENSP00000481204, ENSP00000480659, ENST00000614946, ENSP00000480619, ENSP00000479707, ENSP00000479682, ENSP00000418998, ENST00000622097, ENSP00000478853, ENSP00000479006, ENSG00000167613, ENST00000616612, ENST00000474878, ENST00000620077, ENST00000620726, ENSP00000301193, ENSP00000479649, ENST00000614937, ENSG00000276163, ENSP00000479133, ENST00000348231, ENSP00000478405, ENSG00000278154, ENSG00000276053, ENSG00000274110, ENST00000618434, ENST00000620357, ENSP00000375622, ENSP00000482922, ENST00000610549

PRO

Q6GTX8

Pharos - Targets

Q6GTX8

PDB

7F9N, 3KGR, 7F9L, 7F9M, 3RP1

HMDB Protein

HMDBP07769

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P29350 PTPN6	5	PTPN6 [tertiary granule lumen] (R-HSA-6800952) PTPN6 [extracellular region] (R-HSA-6806315) PTPN6 [specific granule lumen] (R-HSA-6799641) PTPN6 [nucleoplasm] (R-HSA-9008911) PTPN6 [cytosol] (R-HSA-197938)	0.613	5

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