Reactome | PTGES2 [azurophil granule lumen]

PTGES2 [azurophil granule lumen]

Stable Identifier

R-HSA-6799232

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

azurophil granule lumen

Synonyms

Prostaglandin E synthase 2 ecNumber4.1.2.-/ecNumber ecNumber5.3.99.3/ecNumber, PGES2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9H7Z7 PTGES2

Gene Names

PTGES2, C9orf15, PGES2

Chain

chain:1-377, chain:88-377

Reference Genes

BioGPS Gene:80142 PTGES2

COSMIC (genes):PTGES2 PTGES2

CTD Gene:80142 PTGES2

dbSNP Gene:80142 PTGES2

ENSEMBL:ENSG00000148334 PTGES2

HGNC:17822 PTGES2

KEGG:hsa:80142 PTGES2

Monarch:80142 PTGES2

NCBI Gene:80142 PTGES2

OMIM:608152 PTGES2

UCSC:Q9H7Z7 PTGES2

Reference Transcript

Other Identifiers

11741445_a_at

11754934_a_at

17098745

218083_3p_at

218083_PM_at

218083_at

3226341

3226342

3226343

3226344

3226345

3226346

3226347

3226348

3226349

3226350

3226351

3226352

3226353

3226354

3226355

3226356

3226357

3226358

3226359

3226360

3226361

3226362

52037_at

80142

8164362

A_24_P106953

GE87476

GO:0000139

GO:0001516

GO:0003677

GO:0003824

GO:0005515

GO:0005576

GO:0005634

GO:0005737

GO:0005739

GO:0005794

GO:0005829

GO:0006355

GO:0006629

GO:0016020

GO:0016491

GO:0016829

GO:0016853

GO:0019371

GO:0020037

GO:0035578

GO:0036134

GO:0043226

GO:0043295

GO:0045893

GO:0046903

GO:0048471

GO:0050220

HMNXSV003052941

ILMN_2345015

ILMN_2345016

PH_hs_0014937

TC09001623.hg

TC09002805.hg

g13376616_3p_at

g13376616_3p_x_at

Participates

as a member of

Azurophil granule lumen proteins [azurophil granule lumen] (Homo sapiens)

Other forms of this molecule

PTGES2(88-377) [cytosol]

PTGES2 [extracellular region]

Inferred To

pges-2 [azurophil granule lumen] (Caenorhabditis elegans)

mPges2 [azurophil granule lumen] (Drosophila melanogaster)

Ptges2 [azurophil granule lumen] (Rattus norvegicus)

PTGES2 [azurophil granule lumen] (Bos taurus)

PTGES2 [azurophil granule lumen] (Canis familiaris)

PTGES2 [azurophil granule lumen] (Danio rerio)

PTGES2 [azurophil granule lumen] (Gallus gallus)

PTGES2 [azurophil granule lumen] (Mus musculus)

PTGES2 [azurophil granule lumen] (Sus scrofa)

ptges2 [azurophil granule lumen] (Xenopus tropicalis)

Cross References

Guide to Pharmacology - Targets

1378

ENSEMBL

ENST00000338961, ENSG00000148334, ENSP00000345341

OpenTargets

ENSG00000148334

ZINC - Substances

PGES2_HUMAN

ZINC target

Q9H7Z7

PRO

Q9H7Z7

GlyGen

Q9H7Z7

ZINC - Investigational

PGES2_HUMAN

GeneCards

PTGES2

HPA

ENSG00000148334-PTGES2

Pharos - Targets

Q9H7Z7

ZINC - Predictions - Purchasable

PGES2_HUMAN

HMDB Protein

HMDBP05566

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UG63 ABCF2	1	ABCF2 [plasma membrane] (R-HSA-5215945)	0.527	3
UniProt:O14949 UQCRQ	1	UQCRQ [mitochondrial inner membrane] (R-HSA-164283)	0.527	3