TP53 family members bind the CASP1 gene

Stable Identifier
R-HSA-6798082
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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TP53 (p53) (Gupta et al. 2001), TP63 (p63) (Celardo et al. 2013) or TP73 (p73) (Jain et al. 2005) bind the p53 response element in the promoter of the CASP1 (caspase-1) gene.

Literature References
PubMed ID Title Journal Year
11278253 Direct transcriptional activation of human caspase-1 by tumor suppressor p53

Gupta, S, Radha, V, Furukawa, Y, Swarup, G

J. Biol. Chem. 2001
16135520 Role of p73 in regulating human caspase-1 gene transcription induced by interferon-{gamma} and cisplatin

Jain, N, Gupta, S, Sudhakar, Ch, Radha, V, Swarup, G

J. Biol. Chem. 2005
23703390 Caspase-1 is a novel target of p63 in tumor suppression

Celardo, I, Grespi, F, Antonov, A, Bernassola, F, Garabadgiu, AV, Melino, G, Amelio, I

Cell Death Dis 2013
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