NRXNs bind SYTs

Stable Identifier
R-HSA-6794348
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, synaptic vesicle membrane
Synonyms
Neurexins bind synaptotagmins
ReviewStatus
5/5
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NRXNs bind SYTs
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Synaptotagmins (SYTs) are transmembrane proteins involved in membrane trafficking and calcium-dependent exocytosis of synaptic vesicles at the synapse. SYTs may mediate this by binding to presynaptic proteins, the neurexins (NRXNs) (Perin 1994, Hata et al. 1993, Petrenko et al. 1991). The interaction between these two proteins may mediate part of the recognition of presynaptic active sites by synaptic vesicles or may regulate neurotransmitter release (Perin 1996).
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Inferred From
Syt1 binds NRXNs (Bos taurus)
Authored
Garapati, P V  (2015-09-04)
Reviewed
Washbourne, P  (2015-11-09)
Created
Garapati, P V  (2015-09-04)
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