NRXNs bind SYTs

Stable Identifier
R-HSA-6794348
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, synaptic vesicle membrane
Synonyms
Neurexins bind synaptotagmins
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
NRXNs bind SYTs
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Synaptotagmins (SYTs) are transmembrane proteins involved in membrane trafficking and calcium-dependent exocytosis of synaptic vesicles at the synapse. SYTs may mediate this by binding to presynaptic proteins, the neurexins (NRXNs) (Perin 1994, Hata et al. 1993, Petrenko et al. 1991). The interaction between these two proteins may mediate part of the recognition of presynaptic active sites by synaptic vesicles or may regulate neurotransmitter release (Perin 1996).

Participants
Input
Output
Participant Of
hasEvent
Inferred From
Syt1 binds NRXNs (Bos taurus)
Authored
Garapati, P V  (2015-09-04)
Reviewed
Washbourne, P  (2015-11-09)
Created
Garapati, P V  (2015-09-04)