Syt1 binds NRXNs

Stable Identifier
R-BTA-6794340
Type
Reaction [binding]
Species
Bos taurus
Compartment
plasma membrane, synaptic vesicle membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Syt1 binds NRXNs
Affinity chromotagoraphy of brain membrane proteins revealed that synaptotagmin 1 (SYT1) binds with cytoplasmic dimains of neurexins (NRXNs) (Hata et al. 1993).
Literature References
PubMed ID Title Journal Year
8901523 Mirror image motifs mediate the interaction of the COOH terminus of multiple synaptotagmins with the neurexins and calmodulin

Perin, MS

Biochemistry 1996
8132583 The COOH terminus of synaptotagmin mediates interaction with the neurexins

Perin, MS

J. Biol. Chem. 1994
8439414 Interaction of synaptotagmin with the cytoplasmic domains of neurexins

Südhof, TC, Hata, Y, Jahn, R, Davletov, B, Petrenko, AG

Neuron 1993
1881448 Binding of synaptotagmin to the alpha-latrotoxin receptor implicates both in synaptic vesicle exocytosis

Südhof, TC, Ushkaryov, YA, Perin, MS, Geppert, M, Davletov, BA, Petrenko, AG

Nature 1991
Participants
Input
Output
Orthologous Events
NRXNs bind SYTs (Homo sapiens)
Authored
Garapati, P V  (2015-09-04)
Reviewed
Washbourne, P  (2015-11-09)
Created
Garapati, P V  (2015-09-04)
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