RISC loading complex [cytosol]

Stable Identifier
R-HSA-6789244
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Synonyms
TARBP2:DICER1:AGO1,2,3,4
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
19820710 Structural insights into RNA processing by the human RISC-loading complex

Wang, HW, Noland, C, Siridechadilok, B, Taylor, DW, Ma, E, Felderer, K, Doudna, JA, Nogales, E

Nat Struct Mol Biol 2009
23531496 Multiple sensors ensure guide strand selection in human RNAi pathways

Noland, CL, Doudna, JA

RNA 2013
15973356 TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

Chendrimada, TP, Gregory, RI, Kumaraswamy, E, Norman, J, Cooch, N, Nishikura, K, Shiekhattar, R

Nature 2005
23661684 Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing

Lee, HY, Zhou, K, Smith, AM, Noland, CL, Doudna, JA

Nucleic Acids Res. 2013
18178619 In vitro reconstitution of the human RISC-loading complex

MacRae, IJ, Ma, E, Zhou, M, Robinson, CV, Doudna, JA

Proc Natl Acad Sci U S A 2008
Participants
components
Participates
as a component of
as a member of
Inferred To
RISC loading complex [cytosol] (Bos taurus)
RISC loading complex [cytosol] (Caenorhabditis elegans)
RISC loading complex [cytosol] (Canis familiaris)
RISC loading complex [cytosol] (Drosophila melanogaster)
RISC loading complex [cytosol] (Gallus gallus)
RISC loading complex [cytosol] (Mus musculus)
RISC loading complex [cytosol] (Rattus norvegicus)
RISC loading complex [cytosol] (Sus scrofa)
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