Reactome | RISC loading complex [cytosol]

Stable Identifier

R-HSA-6789244

Type

Complex

Species

Homo sapiens

Compartment

cytosol

Synonyms

TARBP2:DICER1:AGO1,2,3,4

Locations in the PathwayBrowser

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Literature References

PubMed ID	Title	Journal	Year
19820710	Structural insights into RNA processing by the human RISC-loading complex Wang, HW, Siridechadilok, B, Ma, E, Noland, C, Felderer, K, Nogales, E, Doudna, JA, Taylor, DW	Nat Struct Mol Biol	2009
23531496	Multiple sensors ensure guide strand selection in human RNAi pathways Doudna, JA, Noland, CL	RNA	2013
15973356	TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing Gregory, RI, Shiekhattar, R, Chendrimada, TP, Norman, J, Nishikura, K, Cooch, N, Kumaraswamy, E	Nature	2005
23661684	Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing Zhou, K, Doudna, JA, Noland, CL, Smith, AM, Lee, HY	Nucleic Acids Res.	2013
18178619	In vitro reconstitution of the human RISC-loading complex Ma, E, Zhou, M, Robinson, CV, Doudna, JA, MacRae, IJ	Proc Natl Acad Sci U S A	2008

Participants

components

Participates

as a component of

as a member of

Inferred To

RISC loading complex [cytosol] (Bos taurus)

RISC loading complex [cytosol] (Gallus gallus)

RISC loading complex [cytosol] (Mus musculus)

RISC loading complex [cytosol] (Sus scrofa)

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