Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
AK4 [mitochondrial matrix]
Stable Identifier
R-HSA-6788783
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
fullName evidence="5"Adenylate kinase 4, mitochondrial, KAD4_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of nucleotides (Homo sapiens)
Interconversion of nucleotide di- and triphosphates (Homo sapiens)
AK4 phosphorylates (d)NMPs to (d)NDPs (Homo sapiens)
AK4 [mitochondrial matrix] (Homo sapiens)
External Reference Information
External Reference
UniProt:P27144 AK4
Gene Names
AK4, AK3, AK3L1
Chain
chain:1-223
Reference Genes
BioGPS Gene:205 AK4
COSMIC (genes):AK4 AK4
CTD Gene:205 AK4
dbSNP Gene:205 AK4
ENSEMBL:ENSG00000162433 AK4
ENSEMBL_homo_sapiens_GENE:ENSG00000162433.15 AK4
HGNC:363 AK4
KEGG Gene (Homo sapiens):205 AK4
Monarch:205 AK4
NCBI Gene:205 AK4
OMIM:103030 AK4
UCSC:P27144 AK4
Reference Transcript
RefSeq:NM_203464.2 AK4
RefSeq:NM_001005353.2 AK4
RefSeq:NM_013410.3 AK4
Other Identifiers
11731833_a_at
11754959_a_at
11758943_s_at
16665674
204347_PM_at
204347_at
204348_PM_s_at
204348_s_at
205
225342_PM_at
225342_at
230630_PM_at
230630_at
2340316
2340317
2340318
2340319
2340320
2340326
2340330
2340331
2340333
2340334
2340335
2340336
2340337
2340338
2340339
2340340
2340341
2340342
2340343
2340344
2340345
32331_at
3449877
3449879
3449880
3449881
3449883
3449884
3449885
3717257
3717258
3717260
3717262
3717264
3717266
3717270
3717272
3717273
3717275
3717277
3717279
48091_at
48822_s_at
65557_at
78361_at
7902038
7962183
A_21_P0013984
A_24_P345290
A_32_P95067
GE62382
GE86076
GO:0000166
GO:0002082
GO:0003824
GO:0004017
GO:0004550
GO:0005515
GO:0005524
GO:0005525
GO:0005737
GO:0005739
GO:0005759
GO:0006091
GO:0006139
GO:0006172
GO:0009117
GO:0009123
GO:0009142
GO:0009188
GO:0015949
GO:0016301
GO:0016310
GO:0016740
GO:0016776
GO:0019205
GO:0043226
GO:0043231
GO:0046033
GO:0046034
GO:0046039
GO:0046899
GO:0046940
GO:0050145
GO:0055086
GO:0071456
GO:1901135
HMNXSV003041482
HMNXSV003048869
Hs.10862.0.S1_3p_at
Hs.274691.0.S2_3p_at
Hs.292805.0.A1_3p_at
ILMN_1686522
ILMN_1764090
ILMN_1777499
ILMN_1798249
ILMN_1843198
ILMN_2338038
PH_hs_0037429
TC01000728.hg
TC01004452.hg
TC12001366.hg
X60673_rna1_at
g8051578_3p_a_at
Inferred To
AKLP2 [mitochondrial matrix]
(Plasmodium falciparum)
AK4 [mitochondrial matrix]
(Bos taurus)
AK4 [mitochondrial matrix]
(Canis familiaris)
AK4 [mitochondrial matrix]
(Danio rerio)
AK4 [mitochondrial matrix]
(Dictyostelium discoideum)
AK4 [mitochondrial matrix]
(Drosophila melanogaster)
AK4 [mitochondrial matrix]
(Gallus gallus)
AK4 [mitochondrial matrix]
(Mus musculus)
AK4 [mitochondrial matrix]
(Plasmodium falciparum)
AK4 [mitochondrial matrix]
(Rattus norvegicus)
AK4 [mitochondrial matrix]
(Saccharomyces cerevisiae)
AK4 [mitochondrial matrix]
(Sus scrofa)
AK4 [mitochondrial matrix]
(Xenopus tropicalis)
Homologues of AK4 [mitochondrial matrix]
(Drosophila melanogaster)
Homologues of AK4 [mitochondrial matrix]
(Plasmodium falciparum)
Dmel\CG15543 [mitochondrial matrix]
(Drosophila melanogaster)
Cross References
RefSeq
NP_001005353.1
,
NP_037542.1
,
NP_982289.1
OpenTargets
ENSG00000162433
IntEnz
2.7.4.6
HPA
ENSG00000162433-AK4
GeneCards
P27144
Ensembl
ENST00000395334
,
ENSG00000162433
,
ENST00000327299
,
ENST00000545314
,
ENSP00000445912
,
ENSP00000322175
,
ENSP00000378743
PRO
P27144
Pharos - Targets
P27144
PDB
3NDP
,
2AR7
,
2BBW
HMDB Protein
HMDBP00586
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P29084 GTF2E2
1
GTF2E2 [nucleoplasm]
(R-HSA-65563)
0.527
2
UniProt:Q8WVK2 SNRNP27
1
SNRNP27 [nucleoplasm]
(R-HSA-6806778)
0.527
2
UniProt:Q5BKU9 OXLD1
0.527
2
UniProt:P13501 CCL5
1
CCL5(24-91) [extracellular region]
(R-HSA-373108)
0.527
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text