TRMT61B methylates adenosine-58 in tRNA yielding 1-methyladenosine-58

Stable Identifier
R-HSA-6787525
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial matrix
ReviewStatus
5/5
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TRMT61B methylates adenosine-58 in tRNA yielding 1-methyladenosine-58
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A TRMT61B oligomer, probably a tetramer, transfers a methyl group from S-adenosylmethionine to the (N)1 position of adenosine-58 in 3 mitochondrial tRNAs (tRNA(Leu)(UUR), tRNA(Lys), tRNA(Ser(UCN)) (Chujo and Suzuki 2012).

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Output
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Event Information
Go Biological Process
mitochondrial tRNA methylation (0070901)
Catalyst Activity

tRNA (adenine-N1-)-methyltransferase activity of TRMT61B tetramer [mitochondrial matrix]

Physical Entity
TRMT61B tetramer [mitochondrial matrix] (Homo sapiens)
Activity
tRNA (adenine-N1-)-methyltransferase activity (GO:0016429)
Authored
May, B  (2015-07-13)
Reviewed
Powell, CA  (2015-11-07)
Levinger, L  (2015-08-11)
Motorin, Y  (2015-08-25)
Jarrous, N  (2015-10-24)
Created
May, B  (2015-07-14)
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