The first step in the formation of both types of IL4 receptor is the binding of Interleukin-4 (IL4) with Interleukin-4 receptor subunit alpha (IL4R) , which has Janus kinase 2 (JAK2) constitutively associated (Hoffman et al. 1995, Shen et al. 1996, Hage et al. 1999).
Shen, BJ, Hage, T, Sebald, W
Hoffman, RC, Castner, BJ, Gerhart, M, Gibson, MG, Rasmussen, BD, March, CJ, Weatherbee, J, Tsang, M, Gustchina, A, Schalk-Hihi, C
Hage, T, Sebald, W, Reinemer, P
© 2021 Reactome