Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
KIAA0391 [mitochondrial matrix]
Stable Identifier
R-HSA-6785725
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
Mitochondrial ribonuclease P protein 3, MRRP3_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the mitochondrion (Homo sapiens)
Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript (Homo sapiens)
mtRNase P [mitochondrial matrix] (Homo sapiens)
KIAA0391 [mitochondrial matrix] (Homo sapiens)
tRNA processing (Homo sapiens)
tRNA modification in the mitochondrion (Homo sapiens)
TRMT10C:HSD17B10 (TRMT10C:SDR5C1) methylates adenosine-9 in tRNA yielding 1-methyladenosine-9 (Homo sapiens)
mtRNase P [mitochondrial matrix] (Homo sapiens)
KIAA0391 [mitochondrial matrix] (Homo sapiens)
TRMT10C:HSD17B10 (TRMT10C:SDR5C1) of mitochondrial RNase P methylates guanosine-9 in tRNA yielding 1-methylguanosine-9 (Homo sapiens)
mtRNase P [mitochondrial matrix] (Homo sapiens)
KIAA0391 [mitochondrial matrix] (Homo sapiens)
tRNA processing in the mitochondrion (Homo sapiens)
Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript (Homo sapiens)
mtRNase P [mitochondrial matrix] (Homo sapiens)
KIAA0391 [mitochondrial matrix] (Homo sapiens)
Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript (Homo sapiens)
mtRNase P [mitochondrial matrix] (Homo sapiens)
KIAA0391 [mitochondrial matrix] (Homo sapiens)
External Reference Information
External Reference
UniProt:O15091 PRORP
Gene Names
PRORP, KIAA0391, MRPP3
Chain
transit peptide:1-45, chain:46-583
Reference Genes
BioGPS Gene:9692 PRORP
COSMIC (genes):KIAA0391 PRORP
CTD Gene:9692 PRORP
dbSNP Gene:9692 PRORP
ENSEMBL:ENSG00000100890 KIAA0391
HGNC:19958 PRORP
Monarch:9692 PRORP
NCBI Gene:9692 PRORP
OMIM:609947 PRORP
UCSC:O15091 PRORP
Reference Transcript
RefSeq:XM_011537409.2 PRORP
RefSeq:XM_017021837.1 PRORP
RefSeq:NM_001256679.1 PRORP
RefSeq:XM_017021836.1 PRORP
RefSeq:XM_005268237.3 PRORP
RefSeq:NM_014672.3 PRORP
RefSeq:NM_001256680.1 PRORP
RefSeq:XM_011537410.2 PRORP
RefSeq:NM_001256681.1 PRORP
RefSeq:XM_017021835.1 PRORP
RefSeq:NM_001256678.1 PRORP
Other Identifiers
11747719_a_at
16783368
202713_PM_s_at
202713_s_at
202714_PM_s_at
202714_s_at
3532394
3532395
3532396
3532397
3532398
3532399
3532401
3532402
3532403
3532404
3532405
3532406
3532407
3532408
3532413
3532426
3532427
3532428
3532429
3532432
3532433
3532434
3532435
3532436
3532437
3532438
3532439
3532440
3532457
40073_at
7973924
9692
A_14_P118617
A_14_P121851
A_14_P135323
A_23_P14340
A_24_P390315
GE80102
GO:0001682
GO:0003824
GO:0004518
GO:0004526
GO:0005515
GO:0005654
GO:0005739
GO:0005759
GO:0006399
GO:0008033
GO:0016787
GO:0030678
GO:0042645
GO:0043226
GO:0043231
GO:0046872
GO:0097745
GO:0140053
GO:0140098
HMNXSV003003335
Hs.154668.0.S1_3p_a_at
ILMN_1701512
PH_hs_0009311
TC14002293.hg
g7662093_3p_a_at
Participates
as a component of
mtRNase P [mitochondrial matrix] (Homo sapiens)
Cross References
ENSEMBL
ENST00000321130
,
ENSP00000474620
,
ENST00000605870
,
ENST00000604948
,
ENSP00000440915
,
ENSP00000474299
,
ENST00000603544
,
ENSP00000324697
,
ENSP00000250377
,
ENSP00000473856
,
ENST00000534898
,
ENST00000250377
OpenTargets
ENSG00000100890
HPA
ENSG00000100890-PRORP
PRO
O15091
Pharos - Targets
O15091
PDB
4XGL
,
8CBK
,
4ROU
,
4XGM
,
7ONU
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text