LCMT2 methoxycarbonylates OHyW-72 yielding OHyW (hydroxywybutosine) at nucleotide 37 of tRNA(Phe)

Stable Identifier
R-HSA-6783473
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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LCMT2 (TYW4) methoxycarbonylates OHyW-72 (7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine) at nucleotide 37 of tRNA(Phe), yielding OHyW (hydroxywybutosine) (Noma et al. 2010).

Literature References
PubMed ID Title Journal Year
20739293 Expanding role of the jumonji C domain as an RNA hydroxylase

Noma, A, Ishitani, R, Kato, M, Nagao, A, Nureki, O, Suzuki, T

J. Biol. Chem. 2010
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Catalyst Activity

tRNA methyltransferase activity of LCMT2 [cytoplasm]

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