Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
LCMT2 [cytoplasm]
Stable Identifier
R-HSA-6782869
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytoplasm
Synonyms
tRNA wybutosine-synthesizing protein 4, TYW4_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
tRNA processing (Homo sapiens)
tRNA modification in the nucleus and cytosol (Homo sapiens)
Synthesis of wybutosine at G37 of tRNA(Phe) (Homo sapiens)
LCMT2 methoxycarbonylates OHyW-72 yielding OHyW (hydroxywybutosine) at nucleotide 37 of tRNA(Phe) (Homo sapiens)
LCMT2 [cytoplasm] (Homo sapiens)
LCMT2 methoxycarbonylates yW-58 yielding yW (wybutosine) at nucleotide 37 of tRNA(Phe) (Homo sapiens)
LCMT2 [cytoplasm] (Homo sapiens)
LCMT2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe) (Homo sapiens)
LCMT2 [cytoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60294 LCMT2
Gene Names
LCMT2, KIAA0547, TYW4
Chain
chain:1-686
Reference Genes
BioGPS Gene:9836 LCMT2
COSMIC (genes):LCMT2 LCMT2
CTD Gene:9836 LCMT2
dbSNP Gene:9836 LCMT2
ENSEMBL:ENSG00000168806 LCMT2
ENSEMBL_homo_sapiens_GENE:ENSG00000168806.8 LCMT2
HGNC:17558 LCMT2
KEGG Gene (Homo sapiens):9836 LCMT2
Monarch:9836 LCMT2
NCBI Gene:9836 LCMT2
OMIM:611246 LCMT2
UCSC:O60294 LCMT2
Reference Transcript
RefSeq:NM_014793.4 LCMT2
Other Identifiers
11723018_at
11749566_s_at
11758091_s_at
16808094
204012_PM_s_at
204012_s_at
3621138
3621139
3621143
3621144
3621145
3621146
3621147
3621148
3621149
3621150
3621151
3621152
3621153
3621155
3621157
7988077
9836
A_23_P106505
GE79140
GO:0003824
GO:0005515
GO:0005737
GO:0006399
GO:0006400
GO:0008033
GO:0008168
GO:0008175
GO:0016740
GO:0030488
GO:0031591
GO:0032259
GO:0140098
GO:1901135
HMNXSV003056777
Hs.200596.0.S1_3p_a_at
ILMN_1667577
PH_hs_0011765
RNA147386|p0490_imsncRNA39
TC15001276.hg
Cross References
RefSeq
NP_055608.2
OpenTargets
ENSG00000168806
HPA
ENSG00000168806-LCMT2
GeneCards
O60294
Ensembl
ENSG00000168806
,
ENSP00000307214
,
ENST00000305641
PRO
O60294
Pharos - Targets
O60294
HMDB Protein
HMDBP09015
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O43707 ACTN4
3
ACTN4 [cytosol]
(R-HSA-390558)
ACTN4 [platelet alpha granule lumen]
(R-HSA-198240)
ACTN4 [extracellular region]
(R-HSA-349729)
0.556
3
UniProt:Q08830 FGL1
0.527
2
UniProt:Q99615 DNAJC7
2
DNAJC7 [cytosol]
(R-HSA-5252099)
DNAJC7 [nucleoplasm]
(R-HSA-5255408)
0.527
2
UniProt:Q9BSL1 UBAC1
1
UBAC1 [cytosol]
(R-HSA-8851644)
0.527
2
UniProt:P29401 TKT
1
TKT [cytosol]
(R-HSA-71321)
0.527
2
UniProt:Q5XPI4 RNF123
2
K63polyUb-RNF123 [cytosol]
(R-HSA-6783055)
RNF123 [cytosol]
(R-HSA-975996)
0.527
3
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text