Reactome | PolyUb-VDAC3 [mitochondrial outer membrane]

PolyUb-VDAC3 [mitochondrial outer membrane]

Stable Identifier

R-HSA-6783045

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial outer membrane

Synonyms

VDAC3, Voltage-dependent anion-selective channel protein 3, VDAC3_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y277 VDAC3

Gene Names

VDAC3

Chain

initiator methionine:1, chain:2-283

Reference Genes

BioGPS Gene:7419 VDAC3

COSMIC (genes):VDAC3 VDAC3

CTD Gene:7419 VDAC3

dbSNP Gene:7419 VDAC3

ENSEMBL:ENSG00000078668 VDAC3

HGNC:12674 VDAC3

KEGG Gene (Homo sapiens):7419 VDAC3

Monarch:7419 VDAC3

NCBI Gene:7419 VDAC3

OMIM:610029 VDAC3

UCSC:Q9Y277 VDAC3

Reference Transcript

Other Identifiers

0000520576

11748014_s_at

11748015_x_at

11754510_s_at

17068541

208845_at

208846_s_at

3096218

3096219

3096221

3096225

3096227

3096228

3096232

3096235

3096238

3096239

3096240

3096241

3096242

3551564

36102_at

7419

8146216

A_23_P60069

A_24_P235316

GE62824

GO:0000166

GO:0003674

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005737

GO:0005739

GO:0005741

GO:0006810

GO:0006811

GO:0008150

GO:0008308

GO:0015288

GO:0015698

GO:0015853

GO:0016020

GO:0016021

GO:0022607

GO:0022857

GO:0032991

GO:0043226

GO:0046930

GO:0055085

GO:0070062

GO:0098656

GO:1902017

HMNXSV003049831

ILMN_1729816

PH_hs_0020870

TC08000327.hg

g2735306_3p_a_at

Participates

as a candidate of

PolyUb-MOM proteins [mitochondrial outer membrane] (Homo sapiens)

Other forms of this molecule

VDAC3 [mitochondrial outer membrane]

Inferred To

vdac3 [mitochondrial outer membrane] (Danio rerio)

VDAC3 [mitochondrial outer membrane] (Canis familiaris)

VDAC3 [mitochondrial outer membrane] (Gallus gallus)

porin [mitochondrial outer membrane] (Drosophila melanogaster)

VDAC5P [mitochondrial outer membrane] (Bos taurus)

Vdac3 [mitochondrial outer membrane] (Mus musculus)

Vdac3 [mitochondrial outer membrane] (Rattus norvegicus)

Modified Residues

Name

ubiquitinylated lysine (PolyUb [mitochondrial outer membrane]) at unknown position

Modification

PolyUb [mitochondrial outer membrane]

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

RefSeq

NP_005653.3, NP_001129166.1

OpenTargets

ENSG00000078668

HPA

ENSG00000078668-VDAC3

GeneCards

Q9Y277

Ensembl

ENST00000521158, ENSG00000078668, ENST00000022615, ENSP00000428845, ENSP00000022615

PRO

Q9Y277

Pharos - Targets

Q9Y277

GlyGen

Q9Y277

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P21796 VDAC1	4	VDAC1 [mitochondrial intermembrane space] (R-HSA-1267960) PolyUb-VDAC1 [mitochondrial outer membrane] (R-HSA-6783079) VDAC1 [mitochondrial outer membrane] (R-HSA-1267988) K48polyUb-VDAC1 [mitochondrial outer membrane] (R-HSA-5205624)	0.564	2