CNIH1, also known as ERV14, is a member of the ERV family of proteins that act as cargo receptors for ER-to-ERGIC trafficking (reviewed in Dancourt and Barlowe, 2010). CNIH1 preferentially interacts with transmembrane proteins like the precursor forms of TFGA and AREG, and mediates their packaging into COPII vesicles by interacting with components of the COPII coat (Castro et al, 2007).
Castro, CP, Piscopo, D, Nakagawa, T, Derynck, R
Dancourt, J, Barlowe, C
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