Cytosolic 7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) specifically hydrolyses N(7)-methylguanosine monophosphate (7MGMP) to 7-methylguanosine (7MG) and inorganic phosphate (Pi). 7MGP is a modified nucleotide byproduct of mRNA turnover and requires degradation as its incorporation into nucleic acids is undesirable (Buschmann et al. 2013).
Schierhorn, A, Lilie, H, Moritz, B, Wahle, E, Jeske, M, Buschmann, J
5'-nucleotidase activity of NT5C3B [cytosol]
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