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RHPN2 [cytosol]
Stable Identifier
R-HSA-5667007
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Rhophilin-2
Icon
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases Activate Rhotekin and Rhophilins (Homo sapiens)
RHOA:GTP binds RHPN1 or RHPN2 (Homo sapiens)
RHOA:GTP:RHPN1,RHPN2 [plasma membrane] (Homo sapiens)
RHPN1,RHPN2 [cytosol] (Homo sapiens)
RHPN2 [cytosol] (Homo sapiens)
RHPN1,RHPN2 [cytosol] (Homo sapiens)
RHPN2 [cytosol] (Homo sapiens)
RHPN2 binds RHOB:GTP (Homo sapiens)
RHOB:GTP:RHPN2 [endosome membrane] (Homo sapiens)
RHPN2 [cytosol] (Homo sapiens)
RHPN2 [cytosol] (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA binds effectors at the plasma membrane (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
RHPN2 [cytosol] (Homo sapiens)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
RHPN2 [cytosol] (Homo sapiens)
RHOB GTPase cycle (Homo sapiens)
RHOB binds effectors on endosomes (Homo sapiens)
RHOB endosome effectors [cytosol] (Homo sapiens)
RHPN2 [cytosol] (Homo sapiens)
RHOB:GTP:RHOB endosome effectors [endosome membrane] (Homo sapiens)
RHOB endosome effectors [cytosol] (Homo sapiens)
RHPN2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8IUC4 RHPN2
Gene Names
RHPN2
Chain
chain:1-686
Reference Genes
BioGPS Gene:85415 RHPN2
COSMIC (genes):RHPN2 RHPN2
CTD Gene:85415 RHPN2
dbSNP Gene:85415 RHPN2
ENSEMBL:ENSG00000131941 RHPN2
HGNC:19974 RHPN2
Monarch:85415 RHPN2
NCBI Gene:85415 RHPN2
OMIM:617932 RHPN2
UCSC:Q8IUC4 RHPN2
Reference Transcript
RefSeq:NM_033103.4 RHPN2
Other Identifiers
11725688_x_at
11725689_a_at
16871202
17121240
17121388
227196_PM_at
227196_at
3612330
3612331
3612332
3612335
3612336
3612341
3612343
3612347
3612349
3612355
3612356
3689263
3689264
3689269
3689271
3689279
3689293
3858853
3858854
3858855
3858856
3858857
3858858
3858859
3858861
3858862
3858863
3858865
3858866
3858868
3858869
3858871
3858873
3858874
3858878
3858886
3858887
60504_at
8035980
85415
A_21_P0011344
A_33_P3387621
GE62931
GO:0003014
GO:0003094
GO:0005515
GO:0005737
GO:0005829
GO:0005886
GO:0007165
GO:0048471
GO:0051497
HMNXSV003029570
Hs.184598.0.S1_3p_at
ILMN_1753143
PH_hs_0032724
TC19001394.hg
Participates
as a member of
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
RHOB endosome effectors [cytosol] (Homo sapiens)
RHPN1,RHPN2 [cytosol] (Homo sapiens)
as a component of
RHOB:GTP:RHPN2 [endosome membrane] (Homo sapiens)
as an input of
RHPN2 binds RHOB:GTP (Homo sapiens)
Inferred To
RHPN2 [cytosol]
(Bos taurus)
RHPN2 [cytosol]
(Canis familiaris)
RHPN2 [cytosol]
(Gallus gallus)
RHPN2 [cytosol]
(Sus scrofa)
Rhpn2 [cytosol]
(Mus musculus)
Rhpn2 [cytosol]
(Rattus norvegicus)
rhpn2 [cytosol]
(Danio rerio)
rhpn2 [cytosol]
(Xenopus tropicalis)
Rhp [cytosol]
(Drosophila melanogaster)
Cross References
ENSEMBL
ENST00000254260
,
ENSP00000254260
OpenTargets
ENSG00000131941
HPA
ENSG00000131941-RHPN2
PRO
Q8IUC4
Pharos - Targets
Q8IUC4
HMDB Protein
HMDBP08165
PDB
2VSV
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q04917 YWHAH
1
YWHAH [cytosol]
(R-HSA-1445107)
0.527
2
UniProt:P61981 YWHAG
1
YWHAG [cytosol]
(R-HSA-380312)
0.527
2
UniProt:Q9BU70 TRMO
0.527
3
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