MT2A binds cadmium

Stable Identifier
R-HSA-5662608
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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MT2A binds cadmium
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The metallothionein MT2A binds 7 atoms of cadmium(II), a cluster of 4 atoms at the alpha domain at the C-terminus and a cluster of 3 atoms at the beta domain at the N-terminus (Pan et al. 1999).
Literature References
PubMed ID Title Journal Year
10542048 Why reversing the sequence of the alpha domain of human metallothionein-2 does not change its metal-binding and folding characteristics

Huang, PC, Zheng, ZF, Lyu, PC, Pan, PK

Eur. J. Biochem. 1999
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Orthologous Events
MT2A binds cadmium (Bos taurus)
MT2A binds cadmium (Canis familiaris)
MT2A binds cadmium (Danio rerio)
MT2A binds cadmium (Gallus gallus)
MT2A binds cadmium (Mus musculus)
MT2A binds cadmium (Rattus norvegicus)
MT2A binds cadmium (Sus scrofa)
Authored
May, B  (2015-01-10)
Reviewed
Atrian, S  (2015-09-19)
Created
May, B  (2015-01-13)
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