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Activated FGFR1 mutants [plasma membrane]
Stable Identifier
R-HSA-5655215
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by FGFR in disease (Homo sapiens)
Signaling by FGFR1 in disease (Homo sapiens)
Activated FGFR1 mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants and fusions bind PLCG1 (Homo sapiens)
Activated FGFR1 mutants and fusions [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants and fusions:PLCG1 [cytosol] (Homo sapiens)
Activated FGFR1 mutants and fusions [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants and fusions phosphorylate PLCG1 (Homo sapiens)
Activated FGFR1 mutants and fusion:p-PLCG1 [cytosol] (Homo sapiens)
Activated FGFR1 mutants and fusions [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants and fusions:PLCG1 [cytosol] (Homo sapiens)
Activated FGFR1 mutants and fusions [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants bind FRS2 (Homo sapiens)
Activated FGFR1 mutants [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants:FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants phosphorylate FRS2 (Homo sapiens)
Activated FGFR1 mutants:FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants:p-FRS2 binds GRB2-SOS1 (Homo sapiens)
Activated FGFR1 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants [plasma membrane] (Homo sapiens)
FGFR1 mutants:p-FRS2:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants:p-FRS2 binds GRB2:GAB1:PIK3R1 (Homo sapiens)
Activated FGFR1 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA (Homo sapiens)
Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
FGFR1 mutants:p-FRS2:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants [plasma membrane] (Homo sapiens)
p-4Y- PLCG1 dissociates from activated FGFR1 mutants and fusions (Homo sapiens)
Activated FGFR1 mutants and fusion:p-PLCG1 [cytosol] (Homo sapiens)
Activated FGFR1 mutants and fusions [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants and fusions [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants [plasma membrane] (Homo sapiens)
Participants
members
Activated overexpressed FGFR1 homodimers [plasma membrane]
(Homo sapiens)
Activated FGFR1 mutant dimers with enhanced kinase activity [plasma membrane]
(Homo sapiens)
Activated FGFR1c P252X mutants [plasma membrane]
(Homo sapiens)
Plasma membrane p-Y FGFR1 fusion dimers [plasma membrane]
(Homo sapiens)
Participates
as a component of
Activated FGFR1 mutants:p-FRS2 [plasma membrane] (Homo sapiens)
Activated FGFR1 mutants:FRS2 [plasma membrane] (Homo sapiens)
as an input of
Activated FGFR1 mutants bind FRS2 (Homo sapiens)
as a member of
Activated FGFR1 mutants and fusions [plasma membrane] (Homo sapiens)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
bone development disease
DOID:0080006
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