Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
MonoUb:K164-PCNA [nucleoplasm]
Stable Identifier
R-HSA-5651984
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
DNA Damage Bypass (Homo sapiens)
Recognition of DNA damage by PCNA-containing replication complex (Homo sapiens)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
USP1:WDR48 binds monoUb:K164-PCNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:USP1:WDR48:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
USP1:WDR48 deubiquitinates monoUb:K164-PCNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:USP1:WDR48:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Homo sapiens)
Termination of translesion DNA synthesis (Homo sapiens)
TRIM25 binds monoUb:164-PCNA (Homo sapiens)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA (Homo sapiens)
USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
Translesion Synthesis by POLH (Homo sapiens)
Elongation by POLH (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
Insertion of correct bases opposite the lesion by POLH (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
SPRTN binds monoUb:K164-PCNA associated with POLH (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Homo sapiens)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Homo sapiens)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
NPLOC4:UFD1L:VPC:SPRTN:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-Template DNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
Translesion synthesis by POLI (Homo sapiens)
POLI incorporates dNMP opposite to damaged DNA base (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
POLZ elongates POLI-incorporated dNMP (Homo sapiens)
POLI:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T-mispaireddNMPs)-DNA Template,(Gamma-HOPdG:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T-mispaireddNMPs)-DNA Template,(Gamma-HOPdG:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
Translesion synthesis by POLK (Homo sapiens)
POLK and POLZ cooperate in elongation of mispaired primer termini (Homo sapiens)
POLK:MonoUb:K164-PCNA:RPA:RFC:(Tg:A-mispaireddNMPs)-DNA Template,(OGUA:A-mispaireddNMPs)-DNA Template,(BPDE-G:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A-mispaireddNMPs)-DNA Template,(OGUA:A-mispaireddNMPs)-DNA Template,(BPDE-G:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
POLK incorporates dNMP opposite to damaged DNA base (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
Translesion synthesis by REV1 (Homo sapiens)
POLZ extends translesion synthesis (Homo sapiens)
POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt-mispairedPolydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
REV1 binds AP-dsDNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
REV1 inserts dCMP opposite to AP sites in DNA (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
REV1 recruits POLZ to (AP:Cyt)-DNA Template (Homo sapiens)
POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
DNA Double-Strand Break Repair (Homo sapiens)
Homology Directed Repair (Homo sapiens)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Homo sapiens)
HDR through Homologous Recombination (HRR) (Homo sapiens)
D-loop extension by DNA polymerases (Homo sapiens)
PCNA:POLD,POLE,POLH,POLK:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:POLH,POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
Nucleotide Excision Repair (Homo sapiens)
Global Genome Nucleotide Excision Repair (GG-NER) (Homo sapiens)
Dual Incision in GG-NER (Homo sapiens)
3'-incision of DNA by ERCC5 (XPG) in GG-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Homo sapiens)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
PCNA homotrimer,MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
Gap-filling DNA repair synthesis and ligation in GG-NER (Homo sapiens)
Ligation of newly synthesized repair patch to incised DNA in GG-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Homo sapiens)
Dual incision in TC-NER (Homo sapiens)
3' incision by ERCC5 (XPG) in TC-NER (Homo sapiens)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Homo sapiens)
PCNA homotrimer,MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
Gap-filling DNA repair synthesis and ligation in TC-NER (Homo sapiens)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Homo sapiens)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer:POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Protein ubiquitination (Homo sapiens)
E3 ubiquitin ligases ubiquitinate target proteins (Homo sapiens)
HLTF binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N (Homo sapiens)
HLTF:monoUb:K164-PCNA:RAD18:UBE2B:Ub:UBE2N:UBE2V2 [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
HLTF polyubiquitinates monoubiquitinated PCNA (Homo sapiens)
HLTF:monoUb:K164-PCNA:RAD18:UBE2B:Ub:UBE2N:UBE2V2 [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
SHPRH:monoUb:K164-PCNA:RAD18:UBE2B:Ub:UBE2N:UBE2V2 [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
SHPRH polyubiquitinates monoubiquitinated PCNA (Homo sapiens)
SHPRH:monoUb:K164-PCNA:RAD18:UBE2B:Ub:UBE2N:UBE2V2 [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
12226657
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
Hoege, C
,
Pfander, B
,
Moldovan, GL
,
Pyrowolakis, G
,
Jentsch, S
Nature
2002
Participants
components
MonoUb-K164-PCNA [nucleoplasm] (Homo sapiens)
Ub [nucleoplasm] (Homo sapiens)
Participant Of
hasComponent
MonoUb:K164,ISG:K164,ISG:K168-PCNA homotrimer [nucleoplasm]
MonoUb:K164-PCNA homotrimer [nucleoplasm]
Inferred To
MonoUb:K164-PCNA [nucleoplasm] (Bos taurus)
MonoUb:K164-PCNA [nucleoplasm] (Caenorhabditis elegans)
MonoUb:K164-PCNA [nucleoplasm] (Canis familiaris)
MonoUb:K164-PCNA [nucleoplasm] (Danio rerio)
MonoUb:K164-PCNA [nucleoplasm] (Dictyostelium discoideum)
MonoUb:K164-PCNA [nucleoplasm] (Drosophila melanogaster)
MonoUb:K164-PCNA [nucleoplasm] (Gallus gallus)
MonoUb:K164-PCNA [nucleoplasm] (Mus musculus)
MonoUb:K164-PCNA [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA [nucleoplasm] (Rattus norvegicus)
MonoUb:K164-PCNA [nucleoplasm] (Saccharomyces cerevisiae)
MonoUb:K164-PCNA [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA [nucleoplasm] (Sus scrofa)
MonoUb:K164-PCNA [nucleoplasm] (Xenopus tropicalis)
© 2020
Reactome
