Reactome | SMYD3 [nucleoplasm]

SMYD3 [nucleoplasm]

Stable Identifier

R-HSA-5637688

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Histone-lysine N-methyltransferase SMYD3, SMYD3_HUMAN, KMT3E

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9H7B4 SMYD3

Gene Names

SMYD3, ZMYND1, ZNFN3A1

Chain

chain:1-428

Reference Genes

BioGPS Gene:64754 SMYD3

COSMIC (genes):SMYD3 SMYD3

CTD Gene:64754 SMYD3

dbSNP Gene:64754 SMYD3

ENSEMBL:ENSG00000185420 SMYD3

HGNC:15513 SMYD3

KEGG:hsa:64754 SMYD3

Monarch:64754 SMYD3

NCBI Gene:64754 SMYD3

OMIM:608783 SMYD3

UCSC:Q9H7B4 SMYD3

Reference Transcript

Other Identifiers

11737982_a_at

11761283_at

218788_PM_s_at

218788_s_at

2464910

2464911

2464912

2464913

2464921

2464927

2464930

2464935

2464936

2464939

2464947

2464956

2464957

2464958

2464959

2464963

2464964

2464969

2464996

2464997

2465001

2465018

2465056

2465066

2465067

2465068

2465069

2465072

2465075

2465099

2465100

2465150

44801_s_at

62937_at

64754

7925589

A_23_P51410

A_32_P103291

GO:0000978

GO:0000993

GO:0001162

GO:0003677

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006325

GO:0006334

GO:0006355

GO:0008168

GO:0014904

GO:0016740

GO:0032259

GO:0033138

GO:0042054

GO:0043226

GO:0045184

GO:0045944

GO:0046872

GO:0048856

GO:0065003

GO:0071549

GO:0140096

GO:0140939

GO:0140954

GO:0140999

HMNXSV003004424

HMNXSV003006993

ILMN_1741954

PH_hs_0000867

g12232400_3p_s_at

Participates

as a candidate of

SUV420H1,SUV420H2,(SMYD3) [nucleoplasm] (Homo sapiens)

as a member of

Inferred To

SET5 [nucleoplasm] (Saccharomyces cerevisiae)

SMYD3 [nucleoplasm] (Bos taurus)

SMYD3 [nucleoplasm] (Canis familiaris)

SMYD3 [nucleoplasm] (Dictyostelium discoideum)

SMYD3 [nucleoplasm] (Gallus gallus)

SMYD3 [nucleoplasm] (Mus musculus)

SMYD3 [nucleoplasm] (Plasmodium falciparum)

SMYD3 [nucleoplasm] (Schizosaccharomyces pombe)

SMYD3 [nucleoplasm] (Sus scrofa)

smyd3 [nucleoplasm] (Danio rerio)

Smyd3 [nucleoplasm] (Drosophila melanogaster)

Smyd3 [nucleoplasm] (Rattus norvegicus)

set-10 [nucleoplasm] (Caenorhabditis elegans)

Cross References

OpenTargets

ENSG00000185420

ENSEMBL

ENSP00000487434, ENSP00000419184, ENSG00000185420, ENST00000630181, ENST00000490107

HPA

ENSG00000185420-SMYD3

GeneCards

SMYD3

PRO

Q9H7B4

Pharos - Targets

Q9H7B4

GlyGen

Q9H7B4

HMDB Protein

HMDBP09037

PDB

3RU0, 5XXD, 5XXJ, 5HI7, 6YUH, 8OWO, 6P6K, 5YJO, 7QNU, 7O2B, 6PAF, 7QNR, 5EX0, 7O2C, 7O2A, 7BJ1, 5EX3, 3PDN, 6IJL, 6ZRB, 5CCM, 6O9O, 5CCL, 3QWP, 6P7Z, 3MEK, 3OXF, 7QLB, 3OXL, 5HQ8, 6P6G, 3OXG, 5V37, 5XXG

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15915 ZIC1	1	ZIC1 [nucleoplasm] (R-HSA-9731648)	0.556	3
UniProt:Q16512 PKN1	3	p-T774-PKN1 [cytosol] (R-HSA-5623651) PKN1 [cytosol] (R-HSA-5623613) p-T774-PKN1 [nucleoplasm] (R-HSA-5625721)	0.556	3
UniProt:Q9UKA8 RCAN3	1	RCAN3 [cytosol] (R-HSA-9728800)	0.527	2
UniProt:P08238 HSP90AB1	6	HSP90AB1 [lysosomal lumen] (R-HSA-9622846) HSP90AB1 [nucleoplasm] (R-HSA-5082399) HSP90AB1 [cytosol] (R-HSA-419617) HSP90AB1 [ficolin-1-rich granule lumen] (R-HSA-6801491) HSP90AB1 [extracellular region] (R-HSA-6806463) HSP90AB1 [secretory granule lumen] (R-HSA-6801477)	0.527	2

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