Reactome | The retrograde IFT train dissociates

The retrograde IFT train dissociates

Stable Identifier

R-HSA-5625424

Type

Reaction [dissociation]

Species

Homo sapiens

Compartment

cilium

ReviewStatus

5/5

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At the base of the cilium, retrograde trains are believed to disassemble and recycle for a subsequent round of IFT transport (Iomini et al, 2001; Buisson et al, 2013; reviewed in Ishikawa et al, 2011; Cole and Snell, 2009).

Literature References

PubMed ID	Title	Journal	Year
21427764	Ciliogenesis: building the cell's antenna Ishikawa, H, Marshall, WF	Nat. Rev. Mol. Cell Biol.	2011
19450523	SnapShot: Intraflagellar transport Cole, DG, Snell, WJ	Cell	2009
11285270	Protein particles in Chlamydomonas flagella undergo a transport cycle consisting of four phases Iomini, C, Babaev-Khaimov, V, Sassaroli, M, Piperno, G	J. Cell Biol.	2001
22992454	Intraflagellar transport proteins cycle between the flagellum and its base Buisson, J, Chenouard, N, Lagache, T, Blisnick, T, Olivo-Marin, JC, Bastin, P	J. Cell. Sci.	2013