ARL13B binds INPP5E

Stable Identifier
R-HSA-5624953
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The small GTPase ARL13B is required for the ciliary localization of INPP5E. ARL13B binds directly to INPP5E and is thought to displace PDE6D from the complex (Humbert et al, 2012).

Literature References
PubMed ID Title Journal Year
23150559 ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting

Humbert, MC, Weihbrecht, K, Searby, CC, Li, Y, Pope, RM, Sheffield, VC, Seo, S

Proc. Natl. Acad. Sci. U.S.A. 2012
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created
Cite Us!