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TRIM5 [cytosol]
Stable Identifier
R-HSA-5624342
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Tripartite motif-containing protein 5 ecNumber6.3.2.-/ecNumber, TRIM5_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Interferon gamma signaling (Homo sapiens)
Expression of IFNG-stimulated genes (Homo sapiens)
IFNG induced TRIMs [cytosol] (Homo sapiens)
TRIM5 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9C035 TRIM5
Gene Names
TRIM5, RNF88
Chain
initiator methionine:, chain:2-493
Reference Genes
BioGPS Gene:85363 TRIM5
COSMIC (genes):TRIM5 TRIM5
CTD Gene:85363 TRIM5
dbSNP Gene:85363 TRIM5
ENSEMBL:ENSG00000132256 TRIM5
ENSEMBL_homo_sapiens_GENE:ENSG00000132256.20 TRIM5
HGNC:16276 TRIM5
KEGG Gene (Homo sapiens):85363 TRIM5
Monarch:85363 TRIM5
NCBI Gene:85363 TRIM5
OMIM:608487 TRIM5
UCSC:Q9C035 TRIM5
Reference Transcript
RefSeq:XM_011520427.1 TRIM5
RefSeq:XM_005253183.2 TRIM5
RefSeq:XM_005253184.2 TRIM5
RefSeq:NM_033034.2 TRIM5
RefSeq:NM_033092.2 TRIM5
RefSeq:NM_033093.2 TRIM5
Other Identifiers
11732590_x_at
11735044_x_at
11751166_a_at
16734929
210705_PM_s_at
210705_s_at
223830_PM_s_at
223830_s_at
3318411
3360627
3360628
3360629
3360630
3360631
3360632
3360633
3360634
3360635
3360638
3360639
3360648
3360649
3360652
3360654
3360655
3360656
3360657
3360658
3360663
3360664
52785_at
7946089
85363
91897_at
A_23_P203505
A_23_P356526
GE566478
GE61825
GO:0000209
GO:0000932
GO:0002218
GO:0002376
GO:0003713
GO:0003824
GO:0004842
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006914
GO:0008270
GO:0010508
GO:0016567
GO:0016740
GO:0019901
GO:0023052
GO:0030674
GO:0031664
GO:0032880
GO:0036211
GO:0038187
GO:0042802
GO:0042803
GO:0043123
GO:0043226
GO:0043410
GO:0044790
GO:0045087
GO:0045893
GO:0046596
GO:0046597
GO:0046872
GO:0051091
GO:0051092
GO:0051607
GO:0060089
GO:0060090
GO:0061630
GO:0070534
GO:0098542
GO:0140096
GO:0140110
GO:1990462
HMNXSV003018797
ILMN_1704972
ILMN_1737599
ILMN_1797359
ILMN_2404665
PH_hs_0032919
TC11001341.hg
TC11003030.hg
g12407382_3p_a_at
g12407386_3p_a_at
Participates
as a member of
IFNG induced TRIMs [cytosol] (Homo sapiens)
Cross References
RefSeq
NP_149023.2
,
XP_005253240.1
,
NP_149083.2
,
XP_011518729.1
,
XP_005253241.1
,
NP_149084.2
OpenTargets
ENSG00000132256
HPA
ENSG00000132256-TRIM5
GeneCards
Q9C035
Ensembl
ENSP00000380058
,
ENST00000684655
,
ENSP00000507420
,
ENST00000380034
,
ENST00000396847
,
ENST00000433961
,
ENSP00000393052
,
ENST00000380027
,
ENSG00000132256
,
ENSP00000369373
,
ENSP00000369366
PRO
Q9C035
Pharos - Targets
Q9C035
HMDB Protein
HMDBP09321
PDB
2YRG
,
2ECV
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.547
3
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