Reactome | CNGB1 [Golgi-associated vesicle membrane]

CNGB1 [Golgi-associated vesicle membrane]

Stable Identifier

R-HSA-5624062

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi-associated vesicle membrane

Synonyms

CNCG2, CNCG3L, CNCG4, RCNC2

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Organelle biogenesis and maintenance (Homo sapiens)

- Cilium Assembly (Homo sapiens)
  - Cargo trafficking to the periciliary membrane (Homo sapiens)
    - VxPx cargo-targeting to cilium (Homo sapiens)
      - Cargo-carrying vesicles bud from the TGN (Homo sapiens)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        CNG tetramer [Golgi-associated vesicle membrane] (Homo sapiens)
        
        CNGB1 [Golgi-associated vesicle membrane] (Homo sapiens)
      - The exocyst complex binds to RAB3IP in the ciliary targeting complex (Homo sapiens)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        CNG tetramer [Golgi-associated vesicle membrane] (Homo sapiens)
        
        CNGB1 [Golgi-associated vesicle membrane] (Homo sapiens)
        
        exocyst complex:RAB8A:GTP:RAB3IP:RAB11:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        CNG tetramer [Golgi-associated vesicle membrane] (Homo sapiens)
        
        CNGB1 [Golgi-associated vesicle membrane] (Homo sapiens)
      - VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane (Homo sapiens)
        
        exocyst complex:RAB8A:GTP:RAB3IP:RAB11:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        CNG tetramer [Golgi-associated vesicle membrane] (Homo sapiens)
        
        CNGB1 [Golgi-associated vesicle membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q14028 CNGB1

Gene Names

CNGB1, CNCG2, CNCG3L, CNCG4, RCNC2

Chain

chain:1-1251

Reference Genes

BioGPS Gene:1258 CNGB1

COSMIC (genes):CNGB1 CNGB1

CTD Gene:1258 CNGB1

dbSNP Gene:1258 CNGB1

ENSEMBL:ENSG00000070729 CNGB1

ENSEMBL_homo_sapiens_GENE:ENSG00000070729.14 CNGB1

HGNC:2151 CNGB1

KEGG Gene (Homo sapiens):1258 CNGB1

Monarch:1258 CNGB1

NCBI Gene:1258 CNGB1

OMIM:600724 CNGB1

UCSC:Q14028 CNGB1

Reference Transcript

Other Identifiers

11733481_at

11735397_at

11735398_a_at

11751941_a_at

1258

16826831

207342_PM_at

207342_at

210769_PM_at

210769_at

211099_PM_s_at

211099_s_at

3693396

3693398

3693400

3693402

3693403

3693404

3693405

3693406

3693407

3693408

3693409

3693410

3693411

3693412

3693413

3693415

3693416

3693417

3693418

3693419

3693422

3693426

3693427

3693428

3693429

3693433

3693435

3693439

3693440

3693441

3693442

3693443

3693445

3693447

3693448

3693450

3693451

3693452

3693453

3693454

3693456

3693457

3693459

3693460

3693461

37071_at

37072_at

8001615

A_23_P37718

A_24_P229588

A_33_P3295738

GE79224

GE886340

GO:0000166

GO:0001750

GO:0001895

GO:0005215

GO:0005222

GO:0005223

GO:0005515

GO:0005886

GO:0005929

GO:0006811

GO:0006812

GO:0007601

GO:0007602

GO:0007608

GO:0010628

GO:0015276

GO:0016020

GO:0017071

GO:0021630

GO:0023052

GO:0030154

GO:0030552

GO:0030553

GO:0030660

GO:0031410

GO:0033365

GO:0034220

GO:0035845

GO:0043195

GO:0043226

GO:0043855

GO:0044877

GO:0045494

GO:0048856

GO:0050877

GO:0050896

GO:0050908

GO:0050911

GO:0051480

GO:0051899

GO:0055065

GO:0055085

GO:0060170

GO:0098655

GO:0099105

GO:1902495

GO:1990834

HMNXSV003015196

HMNXSV003047706

L15296_s_at

PH_hs_0005161

TC16001144.hg

U58837_s_at

g1143724_3p_at

g1518638_3p_a_at

g4502918_3p_at

Participates

as a component of

CNG tetramer [Golgi-associated vesicle membrane] (Homo sapiens)

Other forms of this molecule

CNGB1 [ciliary membrane]

CNGB1 [Golgi membrane]

CNGB1 [plasma membrane]

Inferred To

CNGB1 [Golgi-associated vesicle membrane] (Bos taurus)

CNGB1 [Golgi-associated vesicle membrane] (Canis familiaris)

CNGB1 [Golgi-associated vesicle membrane] (Mus musculus)

CNGB1 [Golgi-associated vesicle membrane] (Rattus norvegicus)

CNGB1 [Golgi-associated vesicle membrane] (Sus scrofa)

CngB [Golgi-associated vesicle membrane] (Drosophila melanogaster)

tax-2 [Golgi-associated vesicle membrane] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001288.3, NP_001273059.1, NP_001129111.1

Guide to Pharmacology - Targets

398

OpenTargets

ENSG00000070729

HPA

ENSG00000070729-CNGB1

GeneCards

Q14028

Ensembl

ENST00000311183, ENST00000564448, ENSG00000070729, ENSP00000251102, ENST00000251102, ENSP00000311670, ENSP00000454633

PRO

Q14028

Pharos - Targets

Q14028

Orphanet

17332

HMDB Protein

HMDBP10837

PDB

7RHI, 8DGK, 7RHJ, 8DGH, 7RHL, 7RH9, 7RHK, 7RHG, 7RHH

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