Reactome | CNGB1 [Golgi-associated vesicle membrane]

CNGB1 [Golgi-associated vesicle membrane]

Stable Identifier

R-HSA-5624062

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi-associated vesicle membrane

Synonyms

CNCG2, CNCG3L, CNCG4, RCNC2

Locations in the PathwayBrowser

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Organelle biogenesis and maintenance (Homo sapiens)

- Cilium Assembly (Homo sapiens)
  - Assembly of the 9+0 primary cilium (Homo sapiens)
    - Cargo trafficking to the periciliary membrane (Homo sapiens)
      - VxPx cargo-targeting to cilium (Homo sapiens)
        
        Cargo-carrying vesicles bud from the TGN (Homo sapiens)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        CNG tetramer [Golgi-associated vesicle membrane] (Homo sapiens)
        
        CNGB1 [Golgi-associated vesicle membrane] (Homo sapiens)
        
        The exocyst complex binds to RAB3IP in the ciliary targeting complex (Homo sapiens)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        CNG tetramer [Golgi-associated vesicle membrane] (Homo sapiens)
        
        CNGB1 [Golgi-associated vesicle membrane] (Homo sapiens)
        
        exocyst complex:RAB8A:GTP:RAB3IP:RAB11:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        CNG tetramer [Golgi-associated vesicle membrane] (Homo sapiens)
        
        CNGB1 [Golgi-associated vesicle membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane (Homo sapiens)
        
        exocyst complex:RAB8A:GTP:RAB3IP:RAB11:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
        
        CNG tetramer [Golgi-associated vesicle membrane] (Homo sapiens)
        
        CNGB1 [Golgi-associated vesicle membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q14028 CNGB1

Gene Names

CNGB1, CNCG2, CNCG3L, CNCG4, RCNC2

Chain

chain:1-1251

Reference Genes

BioGPS Gene:1258 CNGB1

COSMIC - genes:CNGB1 CNGB1

CTD Gene:1258 CNGB1

dbSNP Gene:1258 CNGB1

ENSEMBL:ENSG00000070729 CNGB1

HGNC:2151 CNGB1

KEGG:hsa:1258 CNGB1

Monarch:1258 CNGB1

NCBI Gene:1258 CNGB1

OMIM:600724 CNGB1

UCSC:Q14028 CNGB1

Reference Transcript

Participates

as a component of

CNG tetramer [Golgi-associated vesicle membrane] (Homo sapiens)

Other forms of this molecule

CNGB1 [ciliary membrane]

CNGB1 [Golgi membrane]

CNGB1 [plasma membrane]

Inferred To

CNGB1 [Golgi-associated vesicle membrane] (Bos taurus)

CNGB1 [Golgi-associated vesicle membrane] (Canis familiaris)

CNGB1 [Golgi-associated vesicle membrane] (Gallus gallus)

CNGB1 [Golgi-associated vesicle membrane] (Mus musculus)

CNGB1 [Golgi-associated vesicle membrane] (Rattus norvegicus)

CNGB1 [Golgi-associated vesicle membrane] (Sus scrofa)

CngB [Golgi-associated vesicle membrane] (Drosophila melanogaster)

tax-2 [Golgi-associated vesicle membrane] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001129111.1, NP_001273059.1, NP_001288.3

Guide to Pharmacology - Targets

398

ENSEMBL

ENSP00000454633, ENSG00000070729, ENST00000564448, ENST00000311183, ENSP00000251102, ENST00000251102, ENSP00000311670

OpenTargets

ENSG00000070729

GeneCards

CNGB1

HPA

ENSG00000070729-CNGB1

PRO

Q14028

Pharos - Targets

Q14028

GlyGen

Q14028

Orphanet

CNGB1

HMDB Protein

HMDBP10837

PDB

7RHL, 7RHI, 7RH9, 7RHK, 8DGK, 7RHJ, 7RHH, 7RHG, 8DGH