EGR2 (KROX20) activates HOXB2 expression

Stable Identifier
R-HSA-5617492
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
EGR2 (KROX20) activates HOXB2 expression
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

As inferrred from mouse embryos, EGR2 (KROX20) binds three sites in the 5' region of the HOXB2 gene and activates expression in rhombomere 3 (r3) and r5. HOXB1 activates HOXB2 in r4 and expression is also observed in r6 and r7.

Participants
Input
Output
Participant Of
hasEvent
Inferred From
Egr2 (Krox20) activates Hoxb2 expression (Mus musculus)
Authored
May, B  (2014-08-08)
Rezsohazy, R  (2015-11-15)
Reviewed
Blasi, F  (2015-05-13)
Created
May, B  (2014-08-12)
Cite Us!