CARD9 oligomerizes

Stable Identifier
R-HSA-5607753
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Activated CARD9 localised in lipid rafts may self-associate with other CARD9 molecules (oligomerization). Residues 140-420 of CARD9 contain heptad repeats characteristic of coiled-coil structures that function in protein oligomerization (Bertin et al. 2000).

Literature References
PubMed ID Title Journal Year
19359218 CARD9 versus CARMA1 in innate and adaptive immunity

Hara, H, Saito, T

Trends Immunol. 2009
11053425 CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B

Bertin, J, Guo, Y, Wang, L, Srinivasula, SM, Jacobson, MD, Poyet, JL, Merriam, S, Du, MQ, Dyer, MJ, Robison, KE, DiStefano, PS, Alnemri, ES

J. Biol. Chem. 2000
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