CARD9 oligomerizes

Stable Identifier
R-HSA-5607753
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane, cytosol
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CARD9 oligomerizes
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Activated CARD9 localised in lipid rafts may self-associate with other CARD9 molecules (oligomerization). Residues 140-420 of CARD9 contain heptad repeats characteristic of coiled-coil structures that function in protein oligomerization (Bertin et al. 2000).

Literature References
PubMed ID Title Journal Year
11053425 CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B

Alnemri, ES, Du, MQ, Robison, KE, Srinivasula, SM, DiStefano, PS, Dyer, MJ, Guo, Y, Bertin, J, Merriam, S, Poyet, JL, Jacobson, MD, Wang, L

J. Biol. Chem. 2000
19359218 CARD9 versus CARMA1 in innate and adaptive immunity

Hara, H, Saito, T

Trends Immunol. 2009
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Orthologous Events
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Authored
Garapati, P V  (2014-07-14)
Reviewed
Geijtenbeek, TB  (2014-09-02)
Created
Garapati, P V  (2014-07-14)
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